Hepatotoxicity in Rats Induced by Aqueous Extract of Polygoni Multiflori Radix, Root of<i> Polygonum multiflorum</i> Related to the Activity Inhibition of CYP1A2 or CYP2E1

<div>Flow chart of the drug administration. (a) Control group: water only. (b) PMR group: PMR only. (c) CYP1A2 inhibitor control group: cimetidine only. (d) CYP2E1 inhibitor control group:<i> trans</i>-1,2-dichloroethylene only. (e) CYP1A2 inhibitor + PMR group: cimetidine and PMR. (f) CYP2E1 inhibitor + PMR group:<i> trans</i>-1,2-dichloroethylene and PMR.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1

Figure 1: Hepatotoxicity in Rats Induced by Aqueous Extract of Polygoni Multiflori Radix, Root of<i> Polygonum multiflorum</i> Related to the Activity Inhibition of CYP1A2 or CYP2E1 

Figure 1 | Hepatotoxicity in Rats Induced by Aqueous Extract of Polygoni Multiflori Radix, Root of Polygonum multiflorum Related to the Activity Inhibition of CYP1A2 or CYP2E1 