New Contributions to Asarum Powder on Immunology Related Toxicity Effects in Lung

Figure 2

The effect of Asarun on the RNA level changes in lung tissues of rats. qRT-PCR was performed to detect the mRNA expression of Tmprss6(matriptase 2), Prkag3, Nptx2, Antxr1, Klk11, Rag2, Olr77, Cd7, Il20, LOC69, C6, Ccl20, LOC68, and Cd163 in lungs of rats after intragastric administration with/without Asarum powders. The results showed that Ccl20 was downregulated rather than other upregulated genes in the Asarum group, compared with the control group after intragastric administration with Asarum powders. That may be induced by the toxicity of Asarum. The data were the of at least three independent experiments. All comparisons were performed with WPS office (kingsoft, China), utilizing unpaired t-test with Welch’s correction. Statistical significance was marked as※ while p<0.05. ※represent the significant difference between the Asarum group and control group (p<0.05).