Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2018 (2018), Article ID 1057539, 21 pages
https://doi.org/10.1155/2018/1057539
Review Article

The Efficacy and Safety of Acupuncture for the Treatment of Children with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

1Department of Clinical Korean Medicine, Graduate School, Kyung Hee University, Kyung Hee Dae-ro 26, Dongdaemun-gu, Seoul 02447, Republic of Korea
2Department of Korean Pediatrics, Hospital of Korean Medicine, Pusan National University, Geumo-ro 20, Mulgeum-eup, Yangsan-si, Gyeongsangnam-do 50612, Republic of Korea
3Department of Pediatrics, College of Korean Medicine, Hospital of Semyung University, St. Sangbang 4-63, Chungju City, Chungcheongbuk-do 27429, Republic of Korea
4Department of Neuropsychiatry, College of Korean Medicine, Kyung Hee University, Kyung Hee Dae-ro 26, Dongdaemun-gu, Seoul 02447, Republic of Korea

Correspondence should be addressed to Gyu Tae Chang

Received 25 July 2017; Revised 13 November 2017; Accepted 29 November 2017; Published 11 January 2018

Academic Editor: Deborah A. Kennedy

Copyright © 2018 Boram Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, DSM-5, American Psychiatric Association, Arlington, Va, USA, 5th edition, 2013. View at Publisher · View at Google Scholar
  2. E. Fombonne, “Epidemiology of pervasive developmental disorders,” Pediatric Research, vol. 65, no. 6, pp. 591–598, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. B. Zablotsky, L. I. Black, M. J. Maenner, L. A. Schieve, and S. J. Blumberg, “Estimated Prevalence of Autism and Other Developmental Disabilities Following Questionnaire Changes in the 2014 National Health Interview Survey,” National Health Statistics Reports, no. 87, pp. 1–20, 2015. View at Google Scholar · View at Scopus
  4. M. McVoy and R. Findling, “Child and Adolescent Psychopharmacology Update,” Psychiatric Clinics of North America, vol. 32, no. 1, pp. 111–133, 2009. View at Publisher · View at Google Scholar · View at Scopus
  5. J. T. McCracken, J. McGough, B. Shah et al., “Risperidone in children with autism and serious behavioral problems,” The New England Journal of Medicine, vol. 347, no. 5, pp. 314–321, 2002. View at Publisher · View at Google Scholar · View at Scopus
  6. P. Howlin, I. Magiati, and T. Charman, “Systematic review of early intensive behavioral interventions for children with autism,” American Journal on Intellectual and Developmental Disabilities, vol. 114, no. 1, pp. 23–41, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. J. Virués-Ortega, “Applied behavior analytic intervention for autism in early childhood: meta-analysis, meta-regression and dose-response meta-analysis of multiple outcomes,” Clinical Psychology Review, vol. 30, no. 4, pp. 387–399, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. M. Spreckley and R. Boyd, “Efficacy of applied behavioral intervention in preschool children with autism for improving cognitive, language, and adaptive behavior: a systematic review and meta-analysis,” Journal of Pediatrics, vol. 154, no. 3, pp. 338–344, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. NCCIH Publication No. D347, “Complementary, Alternative, or Integrative Health: What’s In a Name?” 2016, https://nccih.nih.gov/health/integrative-health.
  10. A. A. Owen-Smith, S. Bent, F. L. Lynch et al., “Prevalence and predictors of complementary and alternative medicine use in a large insured sample of children with Autism Spectrum Disorders,” Research in Autism Spectrum Disorders, vol. 17, pp. 40–51, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. N. Klein and K. J. Kemper, “Integrative approaches to caring for children with autism,” Current Problems in Pediatric and Adolescent Health Care, vol. 46, no. 6, pp. 195–201, 2016. View at Publisher · View at Google Scholar · View at Scopus
  12. E. Hanson, L. A. Kalish, E. Bunce et al., “Use of complementary and alternative medicine among children diagnosed with autism spectrum disorder,” Journal of Autism and Developmental Disorders, vol. 37, no. 4, pp. 628–636, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. H. A. Tindle, R. B. Davis, R. S. Phillips, and D. M. Eisenberg, “Trends in use of complementary and alternative medicine by us adults: 1997–2002,” Alternative Therapies in Health and Medicine, vol. 11, no. 1, pp. 42–49, 2015. View at Google Scholar · View at Scopus
  14. Y. Zhang, J. J. Xing, J. Li, B. Y. Zeng, and F. R. Liang, “History of acupuncture research,” in International Review of Neurobiology, vol. 111, chapter 1, pp. 1–23, Elsevier, 2013. View at Publisher · View at Google Scholar
  15. W.-X. Chen, L. Wu-Li, and V. C. N. Wong, “Electroacupuncture for children with autism spectrum disorder: Pilot study of 2 cases,” The Journal of Alternative and Complementary Medicine, vol. 14, no. 8, pp. 1057–1065, 2008. View at Publisher · View at Google Scholar · View at Scopus
  16. G. J. Lee, C. S. Yin, S. K. Choi, J. S. Yang, H. Lee, and H. K. Park, “Acupuncture attenuates extracellular glutamate level in global ischemia model of rat,” Neurological Research, vol. 32, supplement 1, pp. 79–83, 2010. View at Publisher · View at Google Scholar · View at Scopus
  17. Q. Xu, J.-W. Yang, Y. Cao et al., “Acupuncture improves locomotor function by enhancing GABA receptor expression in transient focal cerebral ischemia rats,” Neuroscience Letters, vol. 588, pp. 88–94, 2015. View at Publisher · View at Google Scholar · View at Scopus
  18. C. Toma, A. Hervás, N. Balmaña et al., “Neurotransmitter systems and neurotrophic factors in autism: Association study of 37 genes suggests involvement of DDC,” The World Journal of Biological Psychiatry, vol. 14, no. 7, pp. 516–527, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. L. Y. Li, N. Jiang, and Y. Zhao, “Could acupuncture have a role in the treatment of autism spectrum disorder via modulation of BDNF expression and activation?” Acupuncture in Medicine, vol. 32, no. 6, pp. 503–505, 2014. View at Publisher · View at Google Scholar · View at Scopus
  20. D. K. Cheuk, V. Wong, and W. X. Chen, “Acupuncture for autism spectrum disorders (ASD),” The Cochrane Database of Systematic Reviews, no. 9, Article ID CD007849, 2011. View at Google Scholar · View at Scopus
  21. M. S. Lee, T.-Y. Choi, B.-C. Shin, and E. Ernst, “Acupuncture for children with autism spectrum disorders: a systematic review of randomized clinical trials,” Journal of Autism and Developmental Disorders, vol. 42, no. 8, pp. 1671–1683, 2012. View at Publisher · View at Google Scholar · View at Scopus
  22. J. P. T. Higgins and S. Green, “Cochrane handbook for systematic reviews of interventions,” version 5.1.0, 2011.
  23. D. Moher, A. Liberati, J. Tetzlaff, and D. G. Altman, “Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement,” PLoS Medicine, vol. 6, no. 7, Article ID e1000097, 2009. View at Publisher · View at Google Scholar
  24. M. Borenstein, L. V. Hedges, J. P. T. Higgins, and H. R. Rothstein, “A basic introduction to fixed- effect and random-effects models for meta-analysis,” Research Synthesis Methods, vol. 1, no. 2, pp. 97–111, 2010. View at Publisher · View at Google Scholar
  25. H. Allam, N. G. Eldine, and G. Helmy, “Scalp acupuncture effect on language development in children with autism: a pilot study,” The Journal of Alternative and Complementary Medicine, vol. 14, no. 2, pp. 109–114, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Q. Chen, J. Q. Fang, Y. Wang et al., “Clinical observation of Han's acupoint nerve stimulator (HANS) in the treatment of somnipathy of autistic children,” Medical Innovation of China, vol. 11, no. 15, pp. 124–127, 2014. View at Google Scholar
  27. J. Fan and M. Li, “Efficacy observation of Jin's three needling therapy on autism children with language development disorders,” Bao Jian Wen Hui, vol. 3, no. 5, p. 79, 2016. View at Google Scholar
  28. X. Gao, “Clinical curative effect observation of Jin's three needling therapy for 50 cases of children with autism,” Journal of the Chinese Medical Association, vol. 31, no. 31, pp. 75–77, 2015. View at Google Scholar
  29. J. He, Theoretical and clinical study on treatment of autism with acupuncture, Hunan University of Chinese Medicine, 2006.
  30. N. Li and Z. Liu, “Clinical study on activating brain and opening orifices scalp acupuncture therapy in the treatment of children with autism,” in Proceedings of the The 5th Beijing International Rehabilitation Forum, pp. 382–387, 2011.
  31. L. Li, Y. Jiao, L.-Y. Liu, and C. Huang, “Analysis of the effect that tongue acupuncture combining with comprehensive intervention to children with autism,” Chinese Journal of Child Health Care, vol. 19, no. 5, pp. 477–479, 2011. View at Google Scholar
  32. T. Li, H. Li, and Y. Zhao, “Clinical evaluation of acupuncture treatment for children with autism,” Chinese Journal of Modern Drug Application, vol. 9, no. 16, pp. 260-261, 2015. View at Google Scholar
  33. J. Liao, “Clinical analysis of scalp acupuncture combined with rehabilitation training in the treatment of children with autism spectrum disorder,” China Practical Medicine, vol. 11, no. 22, pp. 268-269, 2016. View at Google Scholar
  34. G. Liu and L. X. Yuan, “Clinical observe of acupuncture treat autism,” Chinese Archives of Traditional Chinese Medicine, vol. 25, no. 12, pp. 2497-2498, 2007. View at Google Scholar
  35. J. G. Sun and X. R. Sun, “Encephalopathy therapeutic tongue acupoint apparatus (ETTAA) for 42 cases of autism,” Chinese acupuncture & moxibustion, vol. 34, no. 1, pp. 96–98, 2014. View at Google Scholar · View at Scopus
  36. Q. Tang, C. Zhang, Y. Wang, D. Xiang, and Y. Zhang, “Clinical observation on treatment of moderate autistic children with combination of scalp point needling and rehabilitation training,” Chinese Journal of Rehabilitation Medicine, vol. 28, no. 3, pp. 251–253, 2013. View at Google Scholar
  37. C. N. Wang, S. Y. Shang, and X. H. Wei, “The influence of electroacupuncture plus behavior therapy on social adaptive behavior ability in autism children,” Shanghai Journal of Acupuncture and Moxibustion, vol. 25, no. 12, p. pp, 2006. View at Google Scholar
  38. C. N. Wang, Y. Liu, X. H. Wei, and L. X. Li, “Effects of electroacupuncture combined with behavior therapy on intelligence and behavior of children of autism,” Chinese acupuncture & moxibustion, vol. 27, no. 9, pp. 660–662, 2007. View at Google Scholar · View at Scopus
  39. J. Wang, J. Li, and X. Mei, “Observation and treatment of children with autism language development disorders efficacy Jin three-needle,” China Continuing Medical Education, vol. 7, no. 22, pp. 159-160, 2015. View at Google Scholar
  40. C. L. Wong, Acupuncture and autism spectrum disorders: an assessor-blinded randomized controlled trial, Hong Kong University of Philosophy, 2008.
  41. V. C. N. Wong and W. X. Chen, “Randomized controlled trial of electro-acupuncture for autism spectrum disorder,” Alternative Medicine Review, vol. 15, no. 2, pp. 136–146, 2010. View at Google Scholar
  42. V. C. N. Wong and J. G. Sun, “Randomized controlled trial of acupuncture versus sham acupuncture in autism spectrum disorder,” The Journal of Alternative and Complementary Medicine, vol. 16, no. 5, pp. 545–553, 2010. View at Publisher · View at Google Scholar · View at Scopus
  43. V. C. Wong, J. Sun, and D. W. Yeung, “Randomized control trial of using tongue acupuncture in autism spectrum disorder,” Journal of Traditional Chinese Medical Sciences, vol. 1, no. 1, pp. 62–72, 2014. View at Publisher · View at Google Scholar
  44. S. Wu, “Observation of the clinical effect of acupuncture treatment of 80 cases of children with autism,” China Health Standard Management, vol. 6, no. 10, p. 246, 2015. View at Google Scholar
  45. Y. Xiong, “Clinical observation of head acupuncture combined with rehabilitation training in the treatment of moderate autism,” Asia-Pacific Traditional Medicine, vol. 10, no. 6, pp. 95-96, 2014. View at Google Scholar
  46. Y. Yang, The clinical research on autism children with treatment of acupuncture on TiaoRentongDu theory, Guangzhou University of Chinese Medicine, 2012.
  47. H. Zeng, S. Chen, X. Yang, X. Huang, X. Zeng, and Q. Luo, “Clinical observation on 30 cases of pediatric autism co-treated with Jin triple-needle therapy,” Journal of Pediatrics of Traditional Chinese Medicine, vol. 10, no. 2, pp. 47–50, 2014. View at Google Scholar
  48. H. Zeng, X. Huang, X. Yang et al., “Clinical study of Jin triple-needle therapy combined with rehabilitation training on childhood autism,” Journal of Pediatrics of Traditional Chinese Medicine, vol. 12, no. 5, pp. 69–75, 2016. View at Google Scholar
  49. N. X. Zhao, F. Gao, W. T. Jiao et al., “Clinical study of the intervention on abnormal behavior in the children with autism treated with head electroacupuncture and special education,” World Journal of Integrated Traditional and Western Medicine, vol. 10, no. 8, pp. 1104–1107, 2015. View at Google Scholar
  50. N. Zhao, N. Zhang, W. Jiao, and F. Gao, “Observations on the efficacy of acupuncture plus Risperidone in improving the abnormal behavior of autistic children,” Shaanxi Journal of Traditional Chinese Medicine, vol. 36, no. 8, pp. 1070-1071, 2015. View at Google Scholar
  51. F. Zhen and Y. Jin, “Clinical efficacy of scalp acupuncture therapy in rehabilitating the language barrier in children with autism,” Journal of Pediatrics of Traditional Chinese Medicine, vol. 12, no. 3, pp. 68–70, 2016. View at Google Scholar
  52. Korea Research Institute of Standards and Science, “The International System of Units (SI) conversion,” http://www.kriss.re.kr/standard/view.do?pg=explanation_tab_06.
  53. M. T. Cabyoglu, N. Ergene, and U. Tan, “The mechanism of acupuncture and clinical applications,” International Journal of Neuroscience, vol. 116, no. 2, pp. 115–125, 2006. View at Publisher · View at Google Scholar · View at Scopus
  54. H. Macpherson, D. G. Altman, R. Hammerschlag et al., “Revised Standards for reporting interventions in clinical trials of acupuncture (STRICTA): Extending the CONSORT Statement,” Acupuncture and Related Therapies, vol. 3, no. 4, pp. 35–46, 2015. View at Google Scholar · View at Scopus
  55. J. P. A. Ioannidis, S. J. W. Evans, P. C. Gøtzsche et al., “Better reporting of harms in randomized trials: an extension of the CONSORT statement,” Annals of Internal Medicine, vol. 141, no. 10, pp. 781–788, 2004. View at Publisher · View at Google Scholar · View at Scopus
  56. N. O. Davis and A. S. Carter, “Parenting stress in mothers and fathers of toddlers with autism spectrum disorders: associations with child characteristics,” Journal of Autism and Developmental Disorders, vol. 38, no. 7, pp. 1278–1291, 2008. View at Publisher · View at Google Scholar · View at Scopus