Preclinical Evaluation of In Vitro and In Vivo Antiviral Activities of KCT-01, a New Herbal Formula against Hepatitis B Virus

Figure 4

In vivo antiviral activity of KCT-01 against HBV. (a-b) Levels of serum HBV DNA (a) and cccDNA from liver tissues (b) were quantified by qPCR assay. Values are provided as mean ± S.D. of triplicated experiments. Statistical significance was processed using Student’s t-test. p < 0.05, p < 0.01, and p < 0.001 compared to control conditions; p < 0.05 compared to ETV single administration group; p < 0.01 compared to KCT-01 single administration group.

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