Neurotrophic Activity of the Carrageenophyte Kappaphycus alvarezii Cultivated at Different Depths and for Different Growth Periods in Various Areas of Indonesia

Table 2

Comparison of the total length of primary neurites (TLPN) in hippocampal neurons exposed to extracts of K. alvarezii grown at different depths and for different culture periods.

Depth (m)	Culture period (days)
	0	15	30	45
0	158 ± 5	115 ± 6	160 ± 5	180 ± 10
1	158 ± 5	100 ± 1	177 ± 6	164 ± 17
2	158 ± 5	100 ± 7	123 ± 6	131 ± 2

Activity (%) is expressed as the mean ± SE (n ≥ 3) relative to the control. Day 0: initial seeding day. Means within each column with different letters (x, y) differ significantly (P < 0.05). Means within each row with different letters (a–c) differ significantly (P < 0.05).