Research Article

Δ3,2-Hydroxybakuchiol Attenuates Depression in Multiple Rodent Models Possibly by Inhibition of Monoamine Transporters in Brain

Figure 2

Δ3,2-hydroxybakuchiol administration decreased the immobility time in the mouse subjected to FST and TST. The tests were performed after male Balb/c mice received 30 min intraperitoneal injections of vehicle solvent, 2.5 mg/kg bupropion, and 2.5, 10, and 40 mg/kg Δ3,2-hydroxybakuchiol, respectively (n =10). (a) Immobility time in TST. (b) Percentage of immobility time (% vehicle) in FST. The data are expressed as mean ± SEM. Compared with vehicle, P < 0.05 and P < 0.01.
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