Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Fig 1

Research Article

Neuroprotective Effects of Gagam-Sipjeondaebo-Tang, a Novel Herbal Formula, against MPTP-Induced Parkinsonian Mice and MPP+-Induced Cell Death in SH-SY5Y Cells

Figure 1

Effects of GST extract on motor functions in MPTP-induced Parkinsonian mice. (a) Timeline of the animal test in this study. Filled arrowheads indicate MPTP injections to induce Parkinsonian mice. Blank arrowheads indicate GST treatment. Dashed arrow shows the day of behavioral test. (b) Effects of GST on the duration of MPTP and control mice stayed on the rotating rod. (c) The result of time spent in the pole test. The time spent before mice arrived on the ground from top of the pole was measured. (d) Western blot shows difference of TH level between control group, MPTP group, and GST administered MPTP group. ## p < 0.01 and ### p < 0.001, compared to control group, p < 0.05 and ∗∗ p < 0.01, compared to MPTP group, analyzed by one-way ANOVA, followed by Bonferroni’s post hoc test.

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