Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Fig 4

Research Article

Effects of Angelica gigas Nakai as an Anti-Inflammatory Agent in In Vitro and In Vivo Atopic Dermatitis Models

Figure 4

Effect of AGNE on protein expression in PMACI-induced HMC-1 cells. Cellular proteins were used to detect (a) I-κBα phosphorylation (cytosol) and (b) DNA-binding activity of NF-κB p65 (nuclear), (c) COX-2 activation, and (d) ERK, (e) JNK, and (f) p38 phosphorylation (cellular hole protein) in HMC-1 cells. Data is means ± SEM of triplicate determinations from separate triplicate experiments ( versus control and versus PMACI alone or DNCB-treated group).