Electroacupuncture Ameliorates Cognitive Deficit and Improves Hippocampal Synaptic Plasticity in Adult Rat with Neonatal Maternal Separation

Figure 2

EA ameliorated spatial learning and memory deficits in rats with neonatal MS. (a) Representative swim paths in target quadrant from each group during the probe trials. The third quadrant is the target quadrant. (b) Increased latency in MS rats to reach the hidden platform in MWM, compared to control, and latency was reduced by repeating EA stimulation, but not MS + Sham-EA. /group; ; , , and versus control group; versus MS group; two-way ANOVA. (c) Reduced percentage of time spent in target quadrant of rats in MS group, compared to rats in control, and percentage of time spent in platform quadrant was increased after EA treatment. /group. ; , versus control group; versus MS group; one-way ANOVA.

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