SYKT Alleviates Doxorubicin-Induced Cardiotoxicity via Modulating ROS-Mediated p53 and MAPK Signal Pathways

<div>Culture and identification of mouse primary cardiomyocytes. (a) After 48 h of incubation, adherent cardiomyocytes accounted for approximately 90% of the cells. The cells exhibited various morphologies, such as spindle and polygonal shapes. After 72 h of incubation, the cells fused together (10×). (b) Cardiomyocytes identification using cTnI immunofluorescent staining (10×).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 1

Figure 1: SYKT Alleviates Doxorubicin-Induced Cardiotoxicity via Modulating ROS-Mediated p53 and MAPK Signal Pathways 