Research Article

Antiviral Activities of Mulberry (Morus alba) Juice and Seed against Influenza Viruses

Figure 2

Antiviral activities of MAJ and MAS against BR59, KR01, BR10, and FL04 in pretreatment of virus. Each virus was mixed with (a) MAJ and (b) MAS for 1 h prior to viral infection. After infection, the cells were washed and overlaid with agarose at 37°C for 72 h. Nontreated influenza virus (IV) and oseltamivir (10 μM) were used as negative and positive controls, respectively. In the pretreatment of virus, oseltamivir showed no inhibitory effect (data not shown). All measurements were performed in triplicate. Within each treatment, an asterisk denotes a significant decrease in the plaque-forming unit (PFU) (log10PFU/mL) to nontreated influenza virus group (P < 0.05).
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