A Hop Extract Lifenol® Improves Postmenopausal Overweight, Osteoporosis, and Hot Flash in Ovariectomized Rats

Table 2

Effects of hop extract (HE) and 17β-estradiol (E2) on the factors affecting bone metabolism in ovariectomized rats.

Treatment	Sham	OVX	Ex	HE30	HE100	E2
17β-Estradiol (pg/ml)	2.9 ± 0.62	0.6 ± 0.44	1.7 ± 0.40	1.8 ± 0.32	2.4 ± 0.74^#	2.6 ± 0.17^#
ALP (U/ml)	49 ± 8.4	99 ± 8.5	63 ± 12.9	57 ± 13.9^#	52 ± 1.8^#	73 ± 5.4
Ca (mg/dl)	10.2 ± 0.34	10.0 ± 0.40	9.5 ± 0.17	9.9 ± 0.11	9.8 ± 0.04	9.8 ± 0.05
P (mg/dl)	5.7 ± 0.71	3.9 ± 0.05	3.9 ± 0.55	4.4 ± 0.37	4.6 ± 0.33	4.3 ± 0.54

OVX: ovariectomy, Ex: scheduled exercise training, HE30: hop extract 30 mg/kg, HE100: hop extract 100 mg/kg, and ALP: alkaline phosphatase. Significantly different from Sham control (P < 0.05). ^#Significantly different from OVX alone (P < 0.05).