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Evidence-Based Complementary and Alternative Medicine
Volume 2018, Article ID 2950758, 10 pages
https://doi.org/10.1155/2018/2950758
Research Article

Antibacterial Activities of Five Medicinal Plants in Ethiopia against Some Human and Animal Pathogens

1Department of Animal Production and Technology, College of Agriculture and Environmental Science, Adigrat University, Adigrat, Ethiopia
2Department of Animal and Range Science, College of Agriculture and Natural Resources, Dilla University, Dilla, Ethiopia
3Department of Chemistry, College of Natural and Computational Science, Dilla University, Dilla, Ethiopia
4Department of Animal and Range Science, Dilla University, Dilla, Ethiopia
5Department of Animal Sciences, College of Agriculture, Aksum University, Shire Campus, Shire, Ethiopia

Correspondence should be addressed to Gebremedhin Romha; moc.oohay@ahmornihdemerbeg

Received 26 August 2017; Revised 13 October 2017; Accepted 14 November 2017; Published 11 January 2018

Academic Editor: Jenny M. Wilkinson

Copyright © 2018 Gebremedhin Romha et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To evaluate the in vitro antibacterial activities of five plant extracts which have been used as traditional medicines by local healers against three multidrug resistant bacteria, namely, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. Results. The highest mean zone of inhibition (4.66 mm) was recorded from methanol extract of Calpurnia aurea (Ait.) Benth. at a concentration of 200 mg/ml against S. aureus, followed by Croton macrostachyus Del. (4.43 mm) at the same dose and solvent for the same bacterial species, while methanol and chloroform extracts of E. brucei Schwein. did not inhibit growth of any bacterial species. The lowest value (100 μg/ml) of minimum inhibitory concentration (MIC) was observed from both methanol and chloroform extracts of C. aurea (Ait.) Benth. against all the three bacteria. The results of the positive control had no statistically significant difference () when compared with crude extracts of C. aurea (Ait.) Benth. at concentration of 200 mg/ml against S. aureus. Conclusion. The results of the present study support the traditional uses of these medicinal plants by the local healers. Except Erythrina brucei Schwein., all the plants investigated in this study exhibited antibacterial activities against the test bacterial species. Further researches are needed to be conducted to evaluate efficacy of these medicinal plant species on other microbes in different agroecological settings and their safety levels as well as their phytochemical compositions.