Research Article

Flavanones from Sedum sarmentosum Bunge Alleviate CCl4-Induced Liver Fibrosis in Rats by Targeting TGF-β1/TβR/Smad Pathway In Turn Inhibiting Epithelial Mesenchymal Transition

Table 2

Effect of FSSB on serum activities of AST, ALT, HA, and LN in CCl4-induced liver fibrosis rats.

GroupsAST (IU·L−1)ALT (IU·L−1)HA (ng·ml−1)LN (ng·ml−1)

Control229.08 ± 50.0758.04 ± 16.4468.69 ± 15.9750.94 ± 16.50
Model485.63 ± 182.1361.05 ± 246.4277.21 ± 110.672.13 ± 8.6
FSSB 310.49 ± 100.1205.28 ± 46.89182.06 ± 38.457.98 ± 13.0
FSSB 200267.90 ± 68.3181.65 ± 58.2161.79 ± 51.553.40 ± 9.0
FSSB 400227.05 ± 78.7171.34 ± 88.4142.59 ± 67.549.30 ± 7.4
Silymarin254.40 ± 50.3180.35 ± 54.3145.83 ± 75.251.82 ± 9.2

Control: the normal control group; model: the model group; FSSB 100: the FSSB 100 mg/kg group; FSSB 200: the FSSB 200 mg/kg group; FSSB 400: the FSSB 400 mg/kg group; silymarin: the silymarin 200 mg/kg group (the same as below). , compared to the normal control group; , , compared to the model group.