Comparative Proteomic Analysis of Two Differently Extracted Coptis chinensis in the Treatment of Type 2 Diabetic Rats

Table 2

Significant differential expressions of proteins in Coptis chinensis-treated rats and the model rats.

Protein accessio	Protein descriptio	Gene name	MW [kDa]	A/M Rati	B/M Rati	D/M Rati	N/M Rati
Glucose Tolerance and Insulin Sensitivity
P35572	Insulin-like growth factor-binding protein 6	Igfbp6	24.193	1.763	2.557	2.181	2.121
A0A0G2JX40	Insulin-like growth factor I	Igf1	16.075	1.422	1.877	1.880	2.001
P21744	Insulin-like growth factor-binding protein 4	Igfbp4	27.745	1.730	2.609	2.527	2.239
F1LRE2	Insulin-like growth factor binding protein, acid labile subunit, isoform CRA_b	Igfals	66.898	1.968	1.973	1.843	2.391
Immunity and Inflammation
P08649	Complement C4	C4	192.16	1.787	1.770	1.868	1.532
Q6MG73	Complement component 2	C2	83.698	1.895	1.748	1.729	1.616
A0A0G2K135	Complement factor I	Cfi	69.774	1.537	1.674	1.808	1.753
Oxidation and Anti-oxidation
A0A0G2JSH9	Peroxiredoxin-2	Prdx2	21.797	1.538	1.723	1.468	2.169
G3V7I0	Peroxiredoxin 3	Prdx3	28.299	2.219	1.992	1.333	2.800
Q5M7T7	Phospholipase A2, group VII (Platelet-activating factor acetylhydrolase, plasma)	Pla2g7	49.49	0.349	0.286	0.234	0.299
Q99ML5	Prenylcysteine oxidase	Pcyox1	56.287	0.530	0.449	0.363	0.371
Lipid Metabolism and Transport
P19939	Apolipoprotein C-I	Apoc1	9.8606	0.498	0.410	0.541	0.581
A0A0G2K8Q1	Apolipoprotein C-III	Apoc3	11.029	0.318	0.284	0.308	0.623
A0A0G2K151	Apolipoprotein E	Apoe	41.199	0.251	0.198	0.203	0.259
F1M6Z1	Apolipoprotein B-100	Apob	509.69	0.426	0.299	0.285	0.286

atabase accession numbers; ame and categories of the proteins identified; atios of treatments/models.