Antidiabetic Activities of Hydromethanolic Leaf Extract of Calpurnia aurea (Ait.) Benth. Subspecies aurea (Fabaceae) in Mice

Table 2

Effect of Calpurnia aurea leaf extract on oral glucose tolerance in normal mice.

Group	Blood glucose level (mg/dl)
	0 min	30 min	60 min	120 min
DW 10 ml/kg	87.06 ± 8.25	202.95 ± 15.84	142.17 ± 15.66	112.45 ± 13.29
CALE 100 mg/kg	85.83 ± 8.55	199.50 ± 15.22	138.06 ± 16.56	84.33 ± 6.94
CALE 200 mg/kg	86.17 ± 5.87	213.00 ± 7.51	137.00 ± 9.01	93.50 ± 5.98
CALE 400 mg/kg	77.61 ± 7.23	211.72 ± 20.84	137.61 ± 14.28	81.94 ± 4.18
GLC 5 mg/kg	81.44 ± 1.24	180.72 ± 8.75	82.83 ± 5.43	61.78 ± 8.59

Each value represents mean ± SEM; n=6 for each treatment. Compared to the negative control, compared to CALE 200mg/kg, compared to baseline blood glucose level, and compared to the blood glucose level at 30 minute. p < 0.05, p < 0.01, and p < 0.001. CALE = Calpurnia aurea leaf extract, DW = distilled water, and GLC = glibenclamide. Time refers to time after oral glucose loading.