Antidiabetic Activities of Hydromethanolic Leaf Extract of Calpurnia aurea (Ait.) Benth. Subspecies aurea (Fabaceae) in Mice

Table 6

Effect of repeated daily doses of hydromethanolic Calpurnia aurea leaf extract on serum lipid level of diabetic mice.

Groups	Serum lipid level (mg/dl)
	TC	TG	HDL-C
Diabetic control	191.33±4.07	164.83±13.49	22.17±3.05
CALE 100 mg/kg	168.83±3.67	154.00±6.71	28.17±2.10
CALE 200 mg/kg	171.67±15.40	154.67±6.28	29.83±3.91
CALE 400 mg/kg	168.87±11.17	148.33±4.68	30.50±1.34
GLC 5 mg/kg	99.50±8.27	77.50±5.55	38.50±2.68
Normal control	83.83±5.36	73.50±7.26	41.17±4.88

Each value represents mean ± SEM; n=6 for each group. Compared to the diabetic control, compared to CALE 100mg/kg, compared to CALE 200 mg/kg, compared to CALE 400mg/kg, and compared to the normal control. p < 0.05, p < 0.01, and p < 0.001. CALE = Calpurnia aurea leaf extract, GLC = glibenclamide, TC = total cholesterol, TG = triglyceride, and HDL-C = high density lipoprotein cholesterol.