Research Article

Electrochemically Reduced Water Delays Mammary Tumors Growth in Mice and Inhibits Breast Cancer Cells Survival In Vitro

Table 3

Complete blood count (CBC) and clinical chemistry parameters in BALB-neuT mice treated with ERW or natural water (CTR).

CBCReference values7 weeks of age11 weeks of age17 weeks of age23 weeks of ageEnd of treatment
CTRERWCTRERWCTRERWCTRERWCTRERW

WBC (103/mm3)5.0-12.05.15.57.5 3.9#5.25.25.33.85.210.5
LYM (103/mm3)4.0-10.03.23.84.6 2.6#2.93.43.02.1 1.46.5
GRAN (103/mm3)0.5-6.01.51.32.21.01.81.41.71.22.92.5
MID (103/mm3)0-2.00.50.40.60.40.50.50.60.50.41.4
LYM (%)50.0-75.063.168.462.766.255.564.957.054.3 34.262.2
GRAN (%)15.0-40.028.923.630.026.335.427.533.135.0 59.130.3
MID (%)5.0-15.08.08.07.37.59.17.69.910.86.87.6
HCT (%)35.0-60.053.552.257.850.854.354.655.647.550.242.7
MCV (μm3)43.0-58.046.246.045.744.845.643.144.1 41.942.839.9
RBC (106/mm3)6.0-12.011.111.312.011.311.912.011.811.311.710.4
HGB (g/dl)9.0-19.016.915.417.517.517.318.918.716.617.815.1
MCH (pg)15.0-19.013.913.6 13.9#15.414.615.015.314.715.214.5
MCHC (g/dl)34.0-39.029.829.6 30.4#34.432.035.234.735.035.536.3
RDW (%)0-99.916.416.515.314.514.915.915.915.515.617.9
MPV (μm3)4.0-7.05.85.85.86.05.75.95.85.86.46.2
PLT (103/mm3)250-1200665.0693.8796.4630.3713.8923.8823.0497.8860.5859.0

Clinical Chemistry

CHOL (mg/dl)50-12078.577.075.457.064.468.059.260.068.091.7
TRI (mg/dl)80-20089.5104.0122.6 54.0# 52.886.798.489.088.0137.3
GOT (U/l)20-250131.081.082.283.090.465.090.0133.067.0123.3
GPT (U/l)20-10047.828.930.230.954.245.446.551.438.531.4
Glucose (mg/dl)60-12065.892.086.677.084.080.068.899.062.0120.0
BUN (mg/dl)10-4028.310.020.222.022.023.823.022.523.022.3

CBC: complete blood count;CTR: control mice;ERW: mice treated with ERW;WBC: white blood cells; LYM: lymphocytes; GRAN: granulocytes; MID: mid-sized cells; HCT: hematocrit; MCV: mean corpuscular volume; RBC: red blood cells; HGB: hemoglobin; MCH: mean corpuscular hemoglobin; MCHC: mean corpuscular hemoglobin concentration; RDW: red cell distribution width; MPV: mean platelet volume; PLT: platelets; CHOL: cholesterol; TRI: triglycerides; GOT: serum Glutamic oxaloacetic transaminase; GPT: serum glutamic pyruvic transaminase; BUN: blood urea nitrogen (p ≤ 0.05, p ≤ 0.01, #p ≤ 0.001 compared with the control mice).