Research Article

Safety and Efficacy of Ferula asafoetida in Functional Dyspepsia: A Randomized, Double-Blinded, Placebo-Controlled Study

Table 4

Statistical comparison of dyspepsia indexing scores.

Name of ToolIntergroup comparison based on independent sample t-testInner group comparison based on paired sample t-test95 CI ValuesMean difference comparison of variables using independent sample t-testp-value
Time of ObservationPlaceboAsafinGroupsBaselineEnd of Study

GSRSBaseline45.33±0.7743.91±0.76Placebo45.09±0.7239.09±0.072.616.00±0.33
End of study39.09±0.6718.90±0.67#Asafin44.19±0.8518.40±0.67#54.9825.28±0.89
GDSSBaseline10.79±0.2010.45±0.21Placebo10.77±0.229.22±0.231.701.90±0.20p<0.001
End of study9.22±0.234.80±0.17Asafin10.47±0.224.80±0.1728.025.66±0.24
NDIBaseline38.95±1.2037.25±0.68Placebo39.09±1.2833.77±1.072.065.38±0.46
End of study33.77±1.0720.71±1.09+Asafin37.28±0.7120.71±1.09+35.0816.57±1.16

Statistical comparison of GSRS, Gastrointestinal Symptom Rating Scale; GDSS, Glasgow Dyspepsia Severity Score; and NDI, Nepean Dyspepsia Index values of Placebo with Asafin using paired sample t-test (within group) and independent sample t-test (between groups). The results are given as mean ± SEM. Values having a superscript significantly differ from its placebo at p<0.001. 95% CI values and mean difference comparison are also given.