Royal Jelly Supplementation Improves Menopausal Symptoms Such as Backache, Low Back Pain, and Anxiety in Postmenopausal Japanese Women
Table 2
Effect of enzyme-treated RJ treatment on menopausal symptoms.
Treatment group
Change compared to baseline
Week 4
Week 8
Week 12
Week 16 (post intervention)
Hot flashes
Placebo
0.208
0.026
0.363
0.372
RJ
Sweating
Placebo
0.272
0.149
0.415
0.533
RJ
Insomnia
Placebo
0.788
0.529
0.961
0.694
RJ
Light sleep
Placebo
0.568
0.752
0.676
0.954
RJ
Irritability
Placebo
0.080
0.207
0.252
0.420
RJ
Anxiety
Placebo
0.067
0.063
0.046
0.229
RJ
Anxious trifles
Placebo
0.343
0.136
0.213
0.645
RJ
Depressive mood
Placebo
0.081
0.125
0.075
0.185
RJ
Fatigue
Placebo
0.576
0.502
0.284
0.475
RJ
Eye strain
Placebo
0.697
0.655
0.885
0.778
RJ
Forgetfulness
Placebo
0.435
0.156
0.373
0.750
RJ
Dizziness
Placebo
0.169
0.091
0.333
0.884
RJ
Palpitation
Placebo
0.978
0.229
0.152
0.587
RJ
Chest tightness
Placebo
0.522
0.312
0.257
0.056
RJ
Headache
Placebo
0.499
0.819
0.602
0.673
RJ
Neck stiffness
Placebo
0.708
0.231
0.805
0.971
RJ
Backache and low back pain
Placebo
0.156
0.440
0.040
0.535
RJ
Joint pain
Placebo
0.719
0.753
0.653
0.723
RJ
Cold hands and feet
Placebo
0.229
0.255
0.247
0.697
RJ
Numbness in the legs or arms
Placebo
0.799
0.937
0.209
0.574
RJ
Sensitive to sounds
Placebo
0.604
0.219
0.098
0.518
RJ
Menopausal symptoms scores were assessed monthly with menopausal symptoms questionnaire of Japanese women (Visual Analog Scale); RJ, enzyme-treated Royal Jelly. All values are mean ± SD.
