Flavonoid Extract from Propolis Inhibits Cardiac Fibrosis Triggered by Myocardial Infarction through Upregulation of SIRT1

Figure 1

FP decreased the expression of myocardial collagen I and collagen III and hydroxyproline content in MI rats. Different concentrations of FP were tested to inhibit the expression of collagen I mRNA (a) or collagen III mRNA (b) and hydroxyproline content (c). Data are expressed as the mean ± SEM; = 6 per group; P < 0.05 versus the sham group; ^#P < 0.05 versus the MI group.

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(b)

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