Effects of Qianlie Tongqiao Capsule on Bladder Weight and Growth Factors in Bladder Tissue of Rats with Testosterone-Induced Benign Prostatic Hyperplasia

Figure 1

Experimental protocol for model establishment and treatment processes. (i) A time interval of 1 week for acclimation of the rats and a total of 40 rats were randomly divided into 5 groups: sham, model, low, middle, and high dosage of Qianlie Tongqiao Capsule (QTC), 8 rats in each group; (ii) a time interval of 1 week in which the sham group underwent sham surgery and the other groups received bilateral orchiectomy, and then all the rats took a postoperation recovery; (iii) a time interval of 4 weeks for inducement of BPH through daily subcutaneous injections of testosterone propionate (TP; 5 mg/kg) dissolved in corn oil (in the sham group, subcutaneous injections of only corn oil); (iv) a time interval of 4 weeks for QTC treatment on the groups along with daily subcutaneous injections of TP (5 mg/kg) dissolved in corn oil; the model group was orally force-fed with sterilized water along with daily subcutaneous injections of TP (5 mg/kg) dissolved in corn oil; the sham group was orally force-fed with sterilized water along with daily subcutaneous injections of corn oil. Finally, all the rats were euthanized.