Exploring the Pharmacological Mechanism of Danzhi Xiaoyao Powder on ER-Positive Breast Cancer by a Network Pharmacology Approach

Figure 4

Compound-compound target network of DXP consists of 374 compound targets and 87 compounds (pink hexagon stands for compound targets; red, orange, yellow, green, blue, and purple circles stand for compounds of Cortex Moutan, Gardeniae Fructus, Radix Bupleuri, Angelicae Sinensis Radix, Paeoniae Radix Alba, and Atractylodes Macrocephala Koidz., respectively. Blue and purple hexagons stand for compounds of Poria Cocos (Schw.) Wolf. and Licorice. Blue diamond stands for common compound of Gardeniae Fructus, Radix Bupleuri, and Angelicae Sinensis Radix. Green diamonds stand for compounds of Cortex Moutan and Paeoniae Radix Alba. Yellow diamond stands for common compound of Gardeniae Fructus, Angelicae Sinensis Radix, and Paeoniae Radix Alba. Orange diamond stands for common compound of Cortex Moutan, Gardeniae Fructus, Radix Bupleuri, and Paeoniae Radix Alba. Red diamond stands for common compound of Cortex Moutan, Gardeniae Fructus, and Radix Bupleuri).