Herba Artemisiae Capillaris Extract Prevents the Development of Streptozotocin-Induced Diabetic Nephropathy of Rat

Table 1

The value of blood glucose, blood lipid, and indicators of renal function after HACE treatment.

	Con + Con	DN + Con	DN + HACE-L	DN + HACE-H	DN + Bena
Glucose (mmol/L)	8.20 ± 1.35	24.07 ± 11.93	30.43 ± 0.93	15.08 ± 11.80	19.67 ± 8.43
BUN (μmol/L)	4.19 ± 0.46	9.58 ± 4.18	10.10 ± 4.62	10.03 ± 5.62	11.43 ± 6.76
CREA (μmol/L)	36.60 ± 2.73	31.30 ± 10.60	39.80 ± 0.52	34.10 ± 5.79	38.15 ± 4.52
Albuminuria (mg)	0.20 ± 0.11	0.50 ± 0.15	0.45 ± 0.21	0.34 ± 0.15	0.34 ± 0.13
T-CHO (mmol/L)	1.84 ± 0.18	2.20 ± 0.48	1.93 ± 0.54	1.61 ± 0.22	1.66 ± 0.15
TG (mmol/L)	1.09 ± 0.34	0.99 ± 0.59	0.72 ± 0.31	0.44 ± 0.19	0.87 ± 0.74
LDL-C (mmol/L)	0.36 ± 0.05	0.62 ± 0.22	0.51 ± 0.08	0.49 ± 0.12	0.48 ± 0.12
HDL-C (mmol/L)	1.18 ± 0.18	1.15 ± 0.31	1.21 ± 0.49	0.92 ± 0.25	0.94 ± 0.17

Twelve weeks after HACE treatment, blood glucose, blood lipid, and renal function parameters of the nondiabetic control group (Con), streptozotocin-induced diabetic group (DN), and the low-dose-HACE-treated (HACE-L) and high-dose-HACE-treated (HACE-H) and benazepril (Bena) positive control groups were tested. Except albuminuria in urine and blood glucose in plasma, other indicators were detected using the blood serum. BUN: blood urea nitrogen; CREA: creatinine; T-CHO: total cholesterol; TG: triglyceride; LDL-C: low-density lipoprotein-cholesterol; HDL-C: high-density lipoprotein-cholesterol. Data are presented as mean ± SD from 10 animals () for each group. versus Con; versus Con; versus DN; versus DN; versus Bena.