Research Article

Danhong Injection Alleviates Mechanical Allodynia via Inhibiting ERK1/2 Activation and Elevates BDNF Level in Sciatic Nerve in Diabetic Rat

Figure 1

Effect of DHI on 50% paw withdraws threshold and ERK1/2 activation in spinal cord after STZ-induced diabetes. DHI or saline treatment was started after 4 weeks of diabetes. (a) Alterations in 50% paw withdraw threshold. (b) Representative western blot result of phosphorylated and total ERK1/2. (c) Phosphorylated ERK1/2 level was first corrected for by total ERK1/2 level and expressed as % control. and versus control group; and versus control group; and versus DPN + saline group. 8~9.
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