A Network Pharmacology-Based Approach to Investigate the Novel TCM Formula against Huntington’s Disease and Validated by Support Vector Machine Model

<div>The modeling structure of LATS1 and validation analysis. (a) The modeling structure of LATS1, and the red square replaces a defined binding site. (b) The 3D-profile validation of modeling structure. The Verify Score, higher than 0, means the trusted simulation of amino acids. (c) Ramachandran plot validation of our modeling structure. The area was divided into three parts; the points stayed at the favoured and allowed implying the ration of modeling structure. (d) All the plots mean the amino acids of binding sites, to find if these important amino acids stood in best or allowed fold region.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 3: A Network Pharmacology-Based Approach to Investigate the Novel TCM Formula against Huntington’s Disease and Validated by Support Vector Machine Model 

Figure 3 | A Network Pharmacology-Based Approach to Investigate the Novel TCM Formula against Huntington’s Disease and Validated by Support Vector Machine Model 