Research Article
Vasorelaxant and Hypotensive Effects of Cheonwangbosimdan in SD and SHR Rats
Table 3
Hypotensive effects of coadministration of amlodipine and CWBSD in SHRs.
| | | Systolic blood pressure (mmHg) | | Time (hour) |
| | dose (mg/kg) | 0 | 0.5 | 1 | 2 | 4 |
| | Amlodipine (5 mg/kg) | 218.8 ± 6.2 | 199.4 ± 6.6 | 199.9 ± 15.1 | 210.7 ± 16.8 | 168.6 ± 1. | | Amlodipine (5 mg/kg) + CWBSD (2,476 mg/kg) | 204.5 ± 12.0 | 194.6 ± 18.4 | 215.5 ± 1.4 | 182.7 ± 12.7 | 138.2 ± 2. |
|
|
Values are expressed as mean ± SEM (n = 5). vs. 0 h group. vs. amlodipine group. |
