Research Article
Ganoderma lucidum and Auricularia polytricha Mushrooms Protect against Carbofuran-Induced Toxicity in Rats
Table 5
Semiquantitative scoring of the architectural changes following histopathological examination of the rat’s liver and kidney.
| | Scoring parameters | Normal control | Positive control-1 | Positive control-2 | Negative control | CF + GL | CF + AP |
| | | Liver |
| | Degeneration of hepatocytes | 1 | 1 | 1 | 3 | 2 | 3 | | Inflammatory cell infiltration | 1 | 1 | 1 | 2 | 1 | 3 | | Vascular congestion | 1 | 1 | 1 | 3 | 2 | 1 | | Edema | 1 | 1 | 1 | 2 | 2 | 2 | | Mean ± SD | | | | | | |
| | | Kidney |
| | Degeneration of tubular epithelium | 1 | 1 | 1 | 2 | 1 | 2 | | Vacuolization | 1 | 1 | 1 | 1 | 1 | 1 | | Glomerular necrosis | 1 | 1 | 1 | 2 | 1 | 1 | | Mean ± SD | | | | | | |
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Scoring was performed as follows: 1 = minimal (<1%), 2 = slight (1–25%), and 3 = moderate (26–50%).
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