Research Article

Supplementation of Stingless Bee Honey from Heterotrigona itama Improves Antiobesity Parameters in High-Fat Diet Induced Obese Rat Model

Table 5

The effects of the stingless bee honey treatment on levels of liver enzymes in SD rats after daily administration of stingless bee honey (SBH) for a period of six weeks.

ParametersGroups
Group 1
(ND)
Group 2
(Obese rats; HFD)
Group 3
(Obese rats; HFD+1000 mg/kg SBH)
Group 4
(Obese rats; HFD+750 mg/kg SBH)
Group 5
(Obese rats; HFD+500 mg/kg SBH)
Group 6
(Obese rats; HFD+ orlistat)

Alkaline Phosphatase (U/L)89.8 ± 4.8187.3 ± 26.9104.2 ± 25.2122.0 ± 9.3140.5 ± 9.0128.3 ± 20.9
Aspartate Aminotransferase (U/L)195.8 ± 14.3389.7 ± 45.7154.5 ± 19.0183.33 ± 18.0206.3 ± 18.9334.5 ± 23.2
Alanine Aminotransferase (U/L)55.0 ± 5.7118.8 ± 32.751.0 ± 4.956.3 ± 5.664.8 ± 8.653.3 ± 2.1

Results are presented as means ± SEM, n = 7.
Values are statistically significant at p < 0.05.
Note: significantly different compared to normal control rats (group 1). Significantly different compared to control obese rats (group 2).
ND: normal diet; HFD: high-fat diet; SBH: stingless bee honey.