Simultaneous Evaluation of the Influence of<i> Panax ginseng</i> on the Pharmacokinetics of Three Diester Alkaloids after Oral Administration of Aconiti Lateralis Radix in Rats Using UHPLC/QQQ-MS/MS

<div>The positive ion peak chromatograms of aconitine, mesaconitine, hypaconitine, and Aconiti Lateralis Radix extracts by UPLC-Q/TOF-MS. (a) aconitine: 646.3220 (m/z); (b) mesaconitine: 632.3021(m/z); (c) hypaconitine: 616.3136 (m/z); and (d) Aconiti Lateralis Radix extracts (1: inositol; 2: fuziline; 3: fuziline; 4: bullatine; 5: talatisamine; 6: benzoylmesaconine; 7: chasmanine; 8: mesaconitine; 9/10: hypaconitine/aconitine; 11: aldohypaconitine).</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 2

Figure 2: Simultaneous Evaluation of the Influence of<i> Panax ginseng</i> on the Pharmacokinetics of Three Diester Alkaloids after Oral Administration of Aconiti Lateralis Radix in Rats Using UHPLC/QQQ-MS/MS 

Figure 2 | Simultaneous Evaluation of the Influence of Panax ginseng on the Pharmacokinetics of Three Diester Alkaloids after Oral Administration of Aconiti Lateralis Radix in Rats Using UHPLC/QQQ-MS/MS 