Simultaneous Evaluation of the Influence of Panax ginseng on the Pharmacokinetics of Three Diester Alkaloids after Oral Administration of Aconiti Lateralis Radix in Rats Using UHPLC/QQQ-MS/MS

Table 3

Standard curves, linear range, correlation coefficient, LOD, and LLOQ of aconitine, mesaconitine, and hypaconitine in rat plasma.

Name	Standard curves	Linear range	R^2	LLOQ	LOD
		(ng/mL)		(ng/mL)	(ng/mL)
Aconitine	y = 0.3651x + 0.0210	0.1-10	0.9997	0.1	0.025
Mesaconitine	y = 0.7952x + 0.0218	0.1-10	0.9987	0.1	0.025
Hypaconitine	y = 0.718x + 0.0605	0.1-10	0.9970	0.1	0.025