Baccharis trimera (Carqueja) Improves Metabolic and Redox Status in an Experimental Model of Type 1 Diabetes

Table 3

Evaluation of initial and final glycaemia, initial and final weight, and insulin in nondiabetic and diabetic rats treated or not with hydroethanolic extract of Baccharis trimera. C: control group; C600: treated control with 600 mg/Kg of extract; C1200: treated control with 1200 mg/Kg of extract; D: non treated diabetic group; D600: treated diabetic with 600 mg/Kg of extract; D1200: treated diabetic with 1200 mg/Kg of extract. Values are expressed as means ± SEM. The statistical analysis was performed between the groups: C x C600; C x C1200; C x D; D x D600; D x D1200. Different letters indicate statistically significant between the compared groups (p< 0.05). Asterisk () indicates differences between the same group, but in relation of initial and final parameter.

Parameters	Experimental groups
	C	C600	C1200	D	D600	D1200
Initial glycemia (mg/dL)	94.88 ± 2.7^b	84.38 ± 2.9^b	93.0 ± 2.8^b	471.9 ± 31.5^a	497.6 ± 42.2	400.7 ± 42.1^a
Final glycemia (mg/dL)	94.97 ± 13.9^b	100.4 ± 7.7^b	99.33 ± 5.7^b	435.3 ± 55.1^a	386.8 ± 33.3	403.9 ± 26.0^a
Initial body weight (g)	177.9 ± 2.6	177.1 ± 2.3	178.2 ± 2.1	185.4 ± 1.7	184.8 ± 1.4	183.8 ± 2.3
Final body weight (g)	170.8 ± 4.0	169.7 ± 2.2	168.1 ± 2.5	160.6 ± 3.7	165.1 ± 6.0	161.2 ± 3.1
Insulin (nmol/L)	0.8579 ± 0.07^b	0.8618 ± 0.02^b	0.8621 ± 0.03^b	0.6479 ± 0.04^c	0.754 ± 0.05^c	0.8792 ± 0.08^a