A Computational Approach Using Bioinformatics to Screening Drug Targets for Leishmania infantum Species

Table 3

List of human proteins interacting with strychnobiflavone predicted by the DRAR-CPI and DDI-CPI servers.

DDI-CPI				DRAR-CPI
PDB ID	Class	Putative target	Docking score	PDB; ID	Putative target	Docking score	-score
3GJW	PD	Poly [ADP-ribose] polymerase 1	−10,6	1MC5	Alcohol dehydrogenase class-3	−612,03	−419,62
2WIJ	PD	Cholinesterase	−10,5	2BH9	Glucose-6-phosphate 1-dehydrogenase	−580,99	−416,22
1QTN	PD	Caspase-8	−10,4	1ORE	Adenine phosphoribosyltransferase	−614,95	−376,09
1O86	PD	Angiotensin-converting enzyme	−10,3	2CG5	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase	−649,52	−376,07
1LD8	PD	Protein farnesyltransferase subunit beta	−10,2	1ZKK	Histone-lysine N-methyltransferase SETD8	−630,85	−371,27
1T5A	PD	Pyruvate kinase isozymes M1/M2	−10,1	1LN1	Phosphatidylcholine transfer protein	−639,55	−370,72
1M13	PD	Nuclear receptor subfamily 1 group I member 2	−10,0	1J8F	NAD-dependent deacetylase sirtuin-2	−542,85	−339,43
1GZ4	PD	NAD-dependent malic enzyme, mitochondrial	−9,7	1HAK	Annexin A5	−513,05	−309,57
2PGJ	PD	ADP-ribosyl cyclase 1	−9,7	1AXN	Annexin A3	−533,45	−302,98
2FZE	PK	Alcohol dehydrogenase class-3	−9,5	1YOW	Steroidogenic factor 1	−593,18	−300,48