Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Tab 1

Research Article

Efficacy and Safety of Indigo Naturalis in Combination with Narrow-Band Ultraviolet B for Treatment of Pityriasis Rosea: A Meta-Analysis

Table 1

Characteristics of the studies included in the meta-analysis.

Author, year casesIntervention and measuresOutcomes
CombinationSingleCombinationSingle

Zhu et al., 2008 [17]4342Compound indigo capsules p.o. 4 tables t.i.d.; dexamethasone (DXM) cream ad us. exts.l.d
NB-UVB irradiation (311 nm): starting irradiation dose 0.39–0.50 J/cm2, increased by 0.1 J/cm2 every time q.o.d.
Compound indigo capsules p.o. 4 tables t.i.d.
Dexamethasone (DXM) cream ad us.exts.l.d
①②③

Wa et al., 2010 [19]3332Compound indigo capsules p.o. 4 tables t.i.d.
NB-UVB irradiation: starting irradiation dose 0.5–0.7 MED increased 0.1 J/cm2  every time q.o.d.
NB-UVB irradiation: starting irradiation dose 0.5–0.7 MED increased by 0.1–0.2 J/cm2  once q.o.d.①②③

Liu et al., 2011 [20]3329/32Compound indigo capsules p.o. 4 tables t.i.d.
NB-UVB irradiation (311–313 nm): starting irradiation dose 0.3–0.5 J/cm2  increased by 10%–20% once q.o.d.
Control group 1: compound indigo capsules p.o. 4 tables t.i.d.
Control group 2: NB-UVB irradiation (311–313 nm): starting irradiation dose 0.3–0.5 J/cm2  increased by 10%–20% once q.o.d.
①②③

Sun et al., 2012 [21]3129Compound indigo pill p.o. 2 g t.i.d.
NB-UVB irradiation (311 nm): starting irradiation dose 0.35 J q.o.d. increased by
0.1 J once q.o.d.
Compound indigo pill p.o. 2 g t.i.d.
①③

Zhao et al., 2012 [22]3938Compound indigo pill p.o. 2 g t.i.d.
NB-UVB irradiation q.o.d., Calamine lotion ad us.ext
NB-UVB irradiation q.o.d., Calamine lotion ad us.ext①②③

Zhao and Sun, 2013 [23]6060Compound indigo capsules p.o. 4 tables t.i.d.
NB-UVB irradiation exposure done 0.2 J/cm2  t.i.w.
Compound indigo capsules p.o. 4 tables t.i.d.
①③

Xu et al., 2014 [24]4042Compound indigo capsules p.o. 4 tables t.i.d.
NB-UVB irradiation (311 nm): starting irradiation dose 0.4–0.6 J/cm2  b.i.w.
NB-UVB irradiation (311 nm): starting irradiation dose 0.4–0.6 J/cm2  b.i.w.①②③

Li, 2014 [25]5451Compound indigo pills p.o. 6 g t.i.d.
NB-UVB irradiation (311 nm): starting irradiation dose 0.4–0.5 J/cm2  q.o.d. increased
Clobetasol propionate ointment
Compound indigo pills p.o. 6 g t.i.d.
Clobetasol propionate ointment
②③

Primary outcome: ① the cure rate; ② the effective rate; and ③ the incidence rate of adverse reaction.