Tou Nong San Attenuates Inflammation in TNBS-IBD Model by Inhibiting NF-κB Signaling Pathway

Figure 5

Histological results of colon tissue. (a) Normal group, (b) model group, (c) TNS (3.3 ml/kg), (d) TNS (6.6 ml/kg), and (e) TNS (13.2 ml/kg). In normal group, the epithelium of colon was integrated and there was no inflammation cell. The black arrows refer to the epithelium of colon. In model group, the epithelium was damaged completely and there were a lot of inflammatory cells. In TNS group, as the dose of TNS increases, the gut barrier was gradually repaired. The extent of inflammation in the mucosa and submucosa was reduced as the dose of TNS increased, as shown by the yellow arrows.

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