Research Article

In Vitro Antidiabetic Effects of Isolated Triterpene Glycoside Fraction from Gymnema sylvestre

Figure 1

% α-glucosidase inhibition and identification of the active fraction TG. (a) shows the % α-glucosidase inhibition of the active fraction III (TG) relative to the positive control acarbose (AC). Values are expressed as mean ± SD. (b) represents the TLC pattern of the active fraction triterpene glycoside (TG labelled as C) and the available commercial standard deacylgymnemic acid (DAC labelled as GA); (c) represents the HPTLC pattern of triterpene glycoside (TG). The active fraction was checked for purity using TLC and HPTLC. TLC spot indicated the presence of gymnemic acid and HPTLC displayed rf value of 0.56. (d) depicts FTIR spectrum of TG. The characteristic FTIR peaks of TG with ester link 1710 cm-1 revealed presence of triterpene glycoside.
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