Guzhi Zengsheng Zhitongwan, a Traditional Chinese Medicinal Formulation, Stimulates Chondrocyte Proliferation through Control of Multiple Genes Involved in Chondrocyte Proliferation and Differentiation
Table 4
Differentially expressed genes that negatively regulate chondrocyte proliferation.
Gene name
Blank (FPKM)
GZZSZTW (FPKM)
log2 fold change (GZZSZTW /Blank)
p value
Rho-related GTP-binding protein RhoB (Rhob)
118.64
53.33
-1.15
1.51E-97
Dual specificity protein phosphatase 6 (Dusp6)
18.05
7.41
-1.28
1.37E-23
Serine/threonine-protein kinase PLK3 (Plk3)
16.41
6.27
-1.39
3.09E-19
Fibroblast growth factor 21 (Fgf21)
14.80
7.37
-1.01
7.27E-05
Cell cycle checkpoint control protein RAD9A (Rad9a)
