Research Article

Tualang Honey Reduced Neuroinflammation and Caspase-3 Activity in Rat Brain after Kainic Acid-Induced Status Epilepticus

Figure 6

5-LOX level in the cerebral cortex, cerebellum, and brainstem of control and KA-induced groups at multiple time points. Graph showed the levels of 5-LOX in the cerebral cortex (a), cerebellum (b), and brainstem (c) at 2 h, 24 h, and 48 h after KA administration in comparison to the relative control groups. Data are presented as Mean ± SEM, n = 6 per group for each time point. Statistical analysis: one-way ANOVA test followed by Tukey post hoc test with p<0.05 indicating significant difference. p<0.05 compared to control group, p<0.05 compared to KA group. ANOVA, one-way analysis of variance; BS, brainstem; CC, cerebral cortex; CB, cerebellum; KA, kainic acid; 5-LOX, 5-lipoxygenase; TH, tualang honey; TPM, topiramate; SEM, the standard error of the mean.
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