Nobiletin Inhibits Hepatic Lipogenesis via Activation of AMP-Activated Protein Kinase

Figure 6

Involvement of AMPK pathway in the inhibitory effects of nobiletin and compound C, an AMPK inhibitor, on lipid accumulation in HepG2 cells. Quantification of accumulated lipids was measured by Oil red O staining. Values are expressed as the means ± standard errors (). versus the control cells, versus high glucose-treated cells, and versus high glucose plus 50 μM nobiletin-treated cells.