Evidence-Based Complementary and Alternative Medicine / 2018 / Article / Tab 3

Research Article

Abyssinone V-4’ Methyl Ether Isolated from Erythrina droogmansiana (Leguminosae) Inhibits Cell Growth and Mammary Glands Hyperplasia Induced in Swiss Mice by the 7,12-Dimethylbenz(a)anthracene

Table 3

Effects of Abyssinone V-4’ methyl etheron relative wet weights of various organs following 28 days of treatments.

OrgansControlDMBADMBA + AVME 10

Uterus1539.63 ± 372.672048.19 ± 184.882165.28 ± 180.21
Liver40621.32 ± 951.3736907.63 ± 373.7144855.91 ± 490.77
Lungs8426.95 ± 422.9510602.41 ± 888.2512583.0 ± 812.51
Spleen4322.87 ± 201.902851.40 ± 380.633420.04 ± 609.28
Adrenals675.79 ± 76.03441.76 ± 69.19571.00 ± 90.5
Kidneys10004.61 ± 801.9111405.62 ± 714.7511153.19 ± 643.13
Femur2572.63 ± 553.632428.19 ± 81.832669.94 ± 124.11
Brain2580.84 ± 111.13052.21 ± 171.222535.22 ± 127.81
Ovaries408.40 ± 70.44321.28 ± 71.22546.60 ± 67.50

Control = normal mice treated with distilled water; DMBA = negative control treated with distilled water; DMBA + AVME 10 = animals treated with the Abyssinone V-4’ methyl etherat the dose of 10 mg/kg. All groups except the normal group (control) received an intragastric dose of DMBA at the dose of 100 mg/kg. Data are represented as mean ± SD (n = 5). and as compared to normal group.