Research Article

Annona muricata Leaf Extract Triggered Intrinsic Apoptotic Pathway to Attenuate Cancerous Features of Triple Negative Breast Cancer MDA-MB-231 Cells

Figure 3

Effects of GLE on cell viability, clonogenicity, and cell cycle. Breast cancer cells were treated with GLE at various concentrations (0, 50, 100, and 200 μg/mL) for 48 hours and their cell viability was measured by MTT assay (a). MDA-MB-231 cells treated with GLE were allowed to grow into visible colony for additional 10 days (b). MDA-MB-231 cells treated with GLE were fixed and sorted by genomic DNA contents (c).
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