Effects of Xin-Ji-Er-Kang on Anticardiovascular Remodeling in L-NAME Induced Hypertensive Mice and Its Potential Mechanisms

Figure 3

Effects of XJEK on cardiac fibrosis in L-NAME induced hypertensive mice. (a) Representative images of histological sections of myocardial fibrosis with VG staining (400x); (b) representative images of histological sections of perivascular fibrosis with VG staining (400x); (c) quantification results of myocardial fibrosis; (d) quantification results of perivascular fibrosis analyzed by Image J as % (mean ± SD, = 8~10). (1) Control group; (2) L-NAME group; (3) L-NAME + XJEK 7.5 g/kg group; (4) L-NAME + Irbesartan 40 mg/kg group. versus control group; ^## versus L-NAME group.

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