Review Article
Role of Acupuncture in the Management of Severe Acquired Brain Injuries (sABIs)
Table 3
Acupuncture and neuroplasticity.
| MAIN MECHANISMS BY WHICH ACUPUNCTURE MAY INFLUENCE THE PHYSIOLOGIC PLASTIC REACTIONS TO BRAIN INJURY |
| (i) Inhibition of brain neuronal apoptosis | (vii) Reduction of blood-brain barrier permeability in intracerebral haemorrhage (caveolin-1/matrix metalloproteinase) |
| (ii) Inhibition of aberrant astrocyte activation | (viii) Regulation of blood lipid metabolism to counteract cerebral free radical damage |
| (iii) Upregulation of neurotrophins expression | (ix) Promoting cerebral vascular immunoinflammatory reactions |
| (iv) Upregulate expression of GDNF | (x) Increase of GABA level |
| (v) Increased functional connectivity | (xi) Reduce contents of excitatory amino acids |
| (vi) Enhanced neuroblast proliferation and differentiation | ā |
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