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Evidence-Based Complementary and Alternative Medicine
Volume 2018, Article ID 8476147, 10 pages
https://doi.org/10.1155/2018/8476147
Research Article

Anti-Inflammatory Effect of Feiyangchangweiyan Capsule on Rat Pelvic Inflammatory Disease through JNK/NF-κB Pathway

1School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712000, China
2College of Chemistry and Pharmacy, Northwest Agriculture and Forestry University, Yangling 712100, China
3Department of Natural Medicine, School of Pharmacy, The Fourth Military Medical University, Xi’an 710032, China
4Shaanxi Junbisha Pharmaceutical Limited Company, Shaanxi, China

Correspondence should be addressed to Yanhua Xie; nc.ude.ummf@hnayeix and Siwang Wang; nc.ude.ummf@wisgnaw

Received 8 November 2017; Revised 22 January 2018; Accepted 24 January 2018; Published 28 February 2018

Academic Editor: Kuzhuvelil B. Harikumar

Copyright © 2018 Yao Li et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. H. Barash, C. Hillson, and E. Buchanan, Suaray M: Pelvic Inflammatory Disease, Humana Press, 2013.
  2. W. Zou, Z. Xiao, X. Wen et al., “The anti-inflammatory effect of Andrographis paniculata (Burm. f.) Nees on pelvic inflammatory disease in rats through down-regulation of the NF-ΚB pathway,” BMC Complementary and Alternative Medicine, vol. 16, no. 1, article no. 483, 2016. View at Publisher · View at Google Scholar · View at Scopus
  3. R. D. V. Miguel, M. Chivukula, U. Krishnamurti et al., “Limitations of the criteria used to diagnose histologic endometritis in epidemiologic pelvic inflammatory disease research,” Pathology - Research and Practice, vol. 207, no. 11, pp. 680–685, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. K. Deb, M. M. Chaturvedi, and Y. K. Jaiswal, “Comprehending the role of LPS in Gram-negative bacterial vaginosis: ogling into the causes of unfulfilled child-wish.,” Archives of Gynecology and Obstetrics, vol. 270, no. 3, pp. 133–146, 2004. View at Publisher · View at Google Scholar · View at Scopus
  5. I. Bernstein-Hanley, J. Coers, Z. R. Balsara, G. A. Taylor, M. N. Starnbach, and W. F. Dietrich, “The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice,” Proceedings of the National Acadamy of Sciences of the United States of America, vol. 103, no. 38, pp. 14092–14097, 2006. View at Publisher · View at Google Scholar · View at Scopus
  6. I. M. Sheldon, D. E. Noakes, A. N. Rycroft, D. U. Pfeiffer, and H. Dobson, “Influence of uterine bacterial contamination after parturition on ovarian dominant follicle selection and follicle growth and function in cattle,” Reproduction, vol. 123, no. 6, pp. 837–845, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. D. Rui, D. Fuhrich, and J. D. C. Ross, “A review of antibiotic therapy for pelvic inflammatory disease,” International Journal of Antimicrobial Agents, vol. 46, no. 3, pp. 272–277, 2015. View at Publisher · View at Google Scholar · View at Scopus
  8. R. Yang, Clinical observation of Feiyang Changweiyan table treat for irritable bowel syndrome, China Modern Medicine, 2012.
  9. M.-C. Lanhers, J. Fleurentin, P. Dorfman, F. Mortier, and J.-M. Pelt, “Analgesic, antipyretic and anti-inflammatory properties of Euphorbia hirta,” Planta Medica, vol. 57, no. 3, pp. 225–231, 1991. View at Publisher · View at Google Scholar · View at Scopus
  10. A. Annamalai, V. L. P. Christina, D. Sudha, M. Kalpana, and P. T. V. Lakshmi, “Green synthesis, characterization and antimicrobial activity of Au NPs using Euphorbia hirta L. leaf extract,” Colloids and Surfaces B: Biointerfaces, vol. 108, pp. 60–65, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. P. Y. Ouyang, C. X. Zhu, G. X. Chen, and L. F. Deng, Preliminary Research of Antimicrobial Activity of the Extract from Polygonum Chinense Linn, Chemistry & Bioengineering, 2012.
  12. M. Kim, S. Choi, K. Park et al., “Anti-oxidative and anti-inflammatory activities of caffeoyl derivatives from the barks of Ilex rotunda,” Planta Medica, vol. 77, no. 12, 2011. View at Publisher · View at Google Scholar
  13. W. Zou, X. Wen, Y. Zheng et al., “Metabolomic Study on the Preventive Effect of Patrinia scabiosaefolia Fisch on Multipathogen Induced Pelvic Inflammatory Disease in Rats,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, Article ID 170792, 2015. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Y. Sutton, M. Sternberg, A. Zaidi, M. E. St. Louis, and L. E. Markowitz, “Trends in pelvic inflammatory disease hospital discharges and ambulatory visits, United States, 1985-2001,” Sexually Transmitted Diseases, vol. 32, no. 12, pp. 778–784, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. T. Darville, “Pelvic inflammatory disease: Identifying research gapsvproceedings of a workshop sponsored by department of health and human services/ national institutes of health/national institute of allergy and infectious diseases, november 3y4, 2011,” Sexually Transmitted Diseases, vol. 40, no. 10, pp. 761–767, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. World Health Organization and Department of Reproductive Health and Research, “Global incidence and prevalence of selected curable sexually transmitted infections: 2008,” Reproductive Health Matters, vol. 20, no. 40, pp. 207–209, 2012. View at Publisher · View at Google Scholar
  17. R. Quentin and R. Verdon, “Microbiologic basis of diagnosis and treatment of pelvic inflammatory disease,” Journal de Gynécologie Obstétrique et Biologie de la Reproduction, vol. 41, no. 8, pp. 850–863, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. S. Saini, N. Gupta, A. Aparna, G. Batra, and D. R. Arora, “Role of anaerobes in acute pelvic inflammatory disease,” Indian Journal of Medical Microbiology, vol. 21, no. 3, pp. 189–192, 2003. View at Google Scholar · View at Scopus
  19. D. Z. Zhang, J. Y. Wen, W. C. Zhou, and W. U. Xiao-Yan, “Pathogenic Bacteria Distribution and Drug Resistance Isolated from Women with Pelvic Inflammatory Disease,” Chinese Journal of Nosocomiology, 2009. View at Google Scholar
  20. C. Mitchell and M. Prabhu, “Pelvic Inflammatory Disease: Current Concepts in Pathogenesis, Diagnosis and Treatment,” Infectious Disease Clinics of North America, vol. 27, no. 4, pp. 793–809, 2013. View at Publisher · View at Google Scholar · View at Scopus
  21. L. L. Fan, W. H. Yu, X. Q. Liu, Z. Cui, J. Ma, and C. P. Li, “A meta-analysis on effectiveness of acupuncture and moxibustion for chronic pelvic inflammatory disease,” Acupuncture Research, vol. 39, no. 2, pp. 156–163, 2014. View at Google Scholar
  22. X. F. Cai, L. F. Chen, Z. L. Wang, and Y. E. Gu, “Effect of acupoint injection by Astragalus injection on local SIgA and pathomorphology changes in rats with chronic pelvic inflammatory disease,” China Journal of Chinese Materia Medica, vol. 31, no. 16, pp. 1361–1364, 2006. View at Google Scholar
  23. J. A. Baron, S. Senn, M. Voelker et al., “Gastrointestinal adverse effects of short-term aspirin use: a meta-analysis of published randomized controlled trials,” Drugs in R&D, vol. 13, no. 1, pp. 9–16, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. D. Geng and R. J. Guo, “TCM symptoms of anxiety disorders studied based on modern literature,” Journal of Beijing University of Traditional Chinese Medicine, vol. 36, no. 7, pp. 484–487, 2013. View at Google Scholar
  25. C. Tortorella, G. Piazzolla, M. Matteo et al., “Interleukin-6, interleukin-1β, and tumor necrosis factor α in menstrual effluents as biomarkers of chronic endometritis,” Fertility and Sterility, vol. 101, no. 1, pp. 242–247, 2014. View at Publisher · View at Google Scholar · View at Scopus
  26. J. G. Cronin, M. L. Turner, L. Goetze, C. E. Bryant, and I. M. Sheldon, “Toll-like receptor 4 and MYD88-dependent signaling mechanisms of the innate immune system are essential for the response to lipopolysaccharide by epithelial and stromal cells of the bovine endometrium,” Biology of Reproduction, vol. 86, no. 2, article no. 51, 2012. View at Publisher · View at Google Scholar · View at Scopus
  27. M. L. Turner, J. G. Cronin, G. D. Healey, and I. M. Sheldon, “Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6,” Endocrinology, vol. 155, no. 4, pp. 1453–1465, 2014. View at Publisher · View at Google Scholar · View at Scopus
  28. W. Cheng, P. Shivshankar, Z. Li, L. Chen, I.-T. Yeh, and G. Zhong, “Caspase-1 contributes to Chlamydia trachomatis-induced upper urogenital tract inflammatory pathologies without affecting the course of infection,” Infection and Immunity, vol. 76, no. 2, pp. 515–522, 2008. View at Publisher · View at Google Scholar · View at Scopus
  29. A. Trunov, O. Obukhova, O. Gorbenko, and A. Shvayk, “Trunova L: Cytokines, estradiol and progesterone in the plasma of women of reproductive age with pelvic inflammatory disease in remission,” in Advances in Bioscience Biotechnology, vol. 4, pp. 727–730, Trunova L, Cytokines, 2013. View at Publisher · View at Google Scholar
  30. S. Gasperini, R. Zambello, C. Agostini et al., “Impaired cytokine production by neutrophils isolated from patients with AIDS,” AIDS, vol. 12, no. 4, pp. 373–379, 1998. View at Publisher · View at Google Scholar · View at Scopus
  31. E. Duvall and A. H. Wyllie, “Death and the cell,” Trends in Immunology, vol. 7, no. 4, pp. 115–119, 1986. View at Publisher · View at Google Scholar · View at Scopus
  32. S. F. Fischer and G. Häcker, “Characterization of Antiapoptotic Activities of Chlamydia pneumoniae in Infected Cells,” Annals of the New York Academy of Sciences, vol. 1010, pp. 565–567, 2003. View at Publisher · View at Google Scholar · View at Scopus
  33. S. F. Fischer, C. Schwarz, J. Vier, and G. Häcker, “Characterization of antiapoptotic activities of Chlamydia pneumoniae in human cells,” Infection and Immunity, vol. 69, no. 11, pp. 7121–7129, 2001. View at Publisher · View at Google Scholar · View at Scopus
  34. Y. Shi, “Mechanisms of caspase activation and inhibition during apoptosis,” Molecular Cell, vol. 9, no. 3, pp. 459–470, 2002. View at Publisher · View at Google Scholar · View at Scopus
  35. A. G. Porter and R. U. Jänicke, “Emerging roles of caspase-3 in apoptosis,” Cell Death & Differentiation, vol. 6, no. 2, pp. 99–104, 1999. View at Publisher · View at Google Scholar · View at Scopus
  36. M. J. Binnicker, R. D. Williams, and M. A. Apicella, “Infection of human urethral epithelium with Neisseria gonorhoeae elicits an upregulation of host anti-apoptotic factors and protects cells from staurosporine-induced apoptosis,” Cellular Microbiology, vol. 5, no. 8, pp. 549–560, 2003. View at Publisher · View at Google Scholar · View at Scopus
  37. M. J. Binnicker, R. D. Williams, and M. A. Apicella, “Gonococcal porin IB activates NF-κB in human urethral epithelium and increases the expression of host antiapoptotic factors,” Infection and Immunity, vol. 72, no. 11, pp. 6408–6417, 2004. View at Publisher · View at Google Scholar · View at Scopus
  38. M. Helenius, M. Hänninen, S. K. Lehtinen, and A. Salminen, “Aging-induced up-regulation of nuclear binding activities of oxidative stress responsive NF-kB transcription factor in mouse cardiac muscle,” Journal of Molecular and Cellular Cardiology, vol. 28, no. 3, pp. 487–498, 1996. View at Publisher · View at Google Scholar · View at Scopus
  39. S. Ghosh, M. J. May, and E. B. Kopp, “NF-κB and rel proteins: evolutionarily conserved mediators of immune responses,” Annual Review of Immunology, vol. 16, pp. 225–260, 1998. View at Publisher · View at Google Scholar · View at Scopus
  40. J. He, X. You, Y. Zeng, M. Yu, L. Zuo, and Y. Wu, “Mycoplasma genitalium-Derived Lipid-Associated Membrane Proteins Activate NF-κB through Toll-Like Receptors 1, 2, and 6 and CD14 in a MyD88-Dependent Pathway,” Clinical and Vaccine Immunology, vol. 16, no. 12, pp. 1750–1757, 2009. View at Publisher · View at Google Scholar · View at Scopus
  41. V. Bours, G. Bonizzi, M. Bentires-Alj et al., “NF-κB activation in response to toxical and therapeutical agents: Role in inflammation and cancer treatment,” Toxicology, vol. 153, no. 1-3, pp. 27–38, 2000. View at Publisher · View at Google Scholar · View at Scopus
  42. T. Into, K. Kiura, M. Yasuda et al., “Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-κB activation,” Cellular Microbiology, vol. 6, no. 2, pp. 187–199, 2004. View at Publisher · View at Google Scholar · View at Scopus
  43. C. L. McGowin, M. Liang, D. H. Martin, and R. B. Pyles, “Mycoplasma genitalium-encoded MG309 activates NF-κB via toll-like receptors 2 and 6 to elicit proinflammatory cytokine secretion from human genital epithelial cells,” Infection and Immunity, vol. 77, no. 3, pp. 1175–1181, 2009. View at Publisher · View at Google Scholar · View at Scopus
  44. T. Shimizu, Y. Kida, and K. Kuwano, “A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-κB through TLR1, TLR2, and TLR6,” The Journal of Immunology, vol. 175, no. 7, pp. 4641–4646, 2005. View at Publisher · View at Google Scholar · View at Scopus
  45. L. Dai, L. Gu, and W. Di, “MiR-199a attenuates endometrial stromal cell invasiveness through suppression of the IKKβ/nf-κb pathway and reduced interleukin-8 expression,” Molecular Human Reproduction, vol. 18, no. 3, Article ID gar066, pp. 136–145, 2012. View at Publisher · View at Google Scholar · View at Scopus
  46. J. Chen, “Multiple signal pathways in obesity-associated cancer,” Obesity Reviews, vol. 12, no. 12, pp. 1063–1070, 2011. View at Publisher · View at Google Scholar · View at Scopus
  47. M. G. Dilshara, K.-T. Lee, R. G. P. T. Jayasooriya et al., “Downregulation of NO and PGE2 in LPS-stimulated BV2 microglial cells by trans-isoferulic acid via suppression of PI3K/Akt-dependent NF-κB and activation of Nrf2-mediated HO-1,” International Immunopharmacology, vol. 18, no. 1, pp. 203–211, 2014. View at Publisher · View at Google Scholar · View at Scopus
  48. Y. Pan, X. Zhang, and Y. Wang, “Targeting JNK by a new curcumin analog to inhibit NF-kB-mediated expression of cell adhesion molecules attenuates renal macrophage infiltration and injury in diabetic mice,” PLoS ONE, vol. 8, no. 11, Article ID e79084, 2013. View at Publisher · View at Google Scholar
  49. W. L. Thompson and L. J. Van Eldik, “Inflammatory cytokines stimulate the chemokines CCL2/MCP-1 and CCL7/MCP-3 through NFκB and MAPK dependent pathways in rat astrocytes,” Brain Research, vol. 1287, pp. 47–57, 2009. View at Publisher · View at Google Scholar
  50. R. Safirstein, J. DiMari, J. Meavesi, and P. Price, “Mechanisms of renal repair and survival following acute injury,” Seminars in Nephrology, vol. 18, no. 5, pp. 519–522, 1998. View at Google Scholar · View at Scopus
  51. F. Xia, C. Wang, Y. Jin et al., “Luteolin protects HUVECs from TNF-α-induced oxidative stress and inflammation via its effects on the Nox4/ROS-NF-κB and MAPK pathways,” Journal of Atherosclerosis and Thrombosis, vol. 21, no. 8, pp. 768–783, 2014. View at Publisher · View at Google Scholar · View at Scopus