An Herbal Medicine, Yukgunja-Tang is more Effective in a Type of Functional Dyspepsia Categorized by Facial Shape Diagnosis: A Placebo-Controlled, Double-Blind, Randomized Trial

Table 1

Inclusion and exclusion criteria of the study.

Inclusion criteria	(1) Subjects aged 19–75 years
	(2) Subjects who meet the Rome III criteria for functional dyspepsia
	(3) Subjects with more than 40 points on the visual analog scale (VAS; 0, no discomfort; 100, most severe discomfort) for the severity of dyspeptic symptoms
	(4) Subjects who agree to receive no other treatments during the study
	(5) Subjects who voluntarily agree with the study protocol and sign a written informed consent
Exclusion criteria	(1) Subjects with peptic ulcer or gastroesophageal reflux disease confirmed on esophagogastroduodenoscopy
	(2) Subjects with obvious signs of irritable bowel syndrome
	(3) Subjects with alarm symptoms, such as severe weight loss, melena, and dysphagia
	(4) Subjects with severe systemic organ diseases (cancer, diseases of heart, lung, liver, or kidney) or mental illness
	(5) Subjects who have had surgery related to the gastrointestinal tract, except for appendectomy more than six months ago
	(6) Subjects taking drugs that might affect the gastrointestinal tract; a minimum wash-out period of a week is required before participating in the study
	(7) Subjects who have had maxillofacial surgery or facial bone contouring surgery
	(8) Subjects who are pregnant or breastfeeding
	(9) Subjects who have malabsorption or maldigestion
	(10) Human immunodeficiency virus (HIV) positive subjects
	(11) Subjects with difficulties in taking part in the study (e.g., serious mental illness, dementia, drug addiction, time constraint, severe disorder in vision or hearing, illiteracy)
	(12) Subjects who have taken investigational drugs for other trials in the last three months