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Evidence-Based Complementary and Alternative Medicine
Volume 2018, Article ID 8608497, 8 pages
Research Article

Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study

1Department of Health and Nutrition, Yamagata Prefectural Yonezawa University of Nutrition Sciences, Yonezawa 992-0025, Japan
2Health Care Food Research Laboratories, Kao Corporation, Tokyo 131-8501, Japan
3R&D, Development Research, Health Care/Household/Chemicals, Kao Corporation, Tochigi 321-3497, Japan

Correspondence should be addressed to Morimasa Kato;

Received 31 July 2017; Revised 8 December 2017; Accepted 24 January 2018; Published 7 March 2018

Academic Editor: Cory S. Harris

Copyright © 2018 Morimasa Kato et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To evaluate the effect of chlorogenic acids (CGAs) intake on cognitive function. Methods. In this pilot study, the Cogstate and CNS Vital Signs test batteries were used to evaluate cognitive function in 8 healthy elderly men and women complaining of subjective memory loss after a 6-month intake of a test beverage containing 330 mg of CGAs just before bedtime. Results. After a 6-month CGA intake period, significant improvement was observed in the One Back Test of the Cogstate, the Shifting Attention Test, and Finger Tapping Test as well as in the composite memory, verbal memory, complex attention, cognitive flexibility, executive function, and motor speed domains of the CNS Vital Signs test battery. Conclusion. A 6-month intake of CGAs may improve attentional, executive, and memory functions in the elderly with complaints of subjective memory loss.