Total Flavonoids from Carya cathayensis Sarg. Leaves Alleviate H9c2 Cells Hypoxia/Reoxygenation Injury via Effects on miR-21 Expression, PTEN/Akt, and the Bcl-2/Bax Pathway

Figure 11

miR-21 expression affected Bcl-2/Bax, caspase3, and cleaved-caspase3 protein expression. (a-f) Representative images of WB analysis and the semiquantification of Bcl-2/Bax, caspase3, and cleaved-caspase3 expression in H9c2 cells were shown. All values are expressed as the mean±SEM (n=3). p<0.01 and p<0.01 vs. control group, p<0.05 and p<0.01 vs. H/R group. p<0.01 and p<0.01 vs. H/R+TFs (10ug/ml) group, p<0.01 and p<0.01 vs. H/R+miR-21 mimic group, and p<0.01 and p<0.01 vs. H/R+miR-21 mimic+TFs (10ug/ml) group.

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