Sirt1/Foxo Axis Plays a Crucial Role in the Mechanisms of Therapeutic Effects of Erzhi Pill in Ovariectomized Rats

Figure 7

EZP upregulated protein levels of Sirt1, Runx2, Foxo1, and Foxo3a and downregulated protein level of PPAR-γ. Results of western blot analysis show the expressions of proteins of Sirt1, Runx2, Foxo1, Foxo3a, and PPAR-γ affected by EZP administration (a–g). β-actin was used as the internal control for the quantification analysis. Data are the means ± standard deviation (SD) and SD is shown as vertical bars. means P<0.05; means P<0.01.

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