Research Article

Discovery of a Novel ERp57 Inhibitor as Antiplatelet Agent from Danshen (Salvia miltiorrhiza)

Figure 5

Rosmarinic acid inhibited the catalytic activity of ERp57. Effects of rosmarinic acid and daucosterol at 3, 10, 30, 100, and 300 μM on ERp57 activity, as determined by insulin reduction assay. Rosmarinic acid, but not daucosterol, inhibited the activity of ERp57 in a concentration-dependent manner.