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Evidence-Based Complementary and Alternative Medicine
Volume 2018, Article ID 9602525, 12 pages
https://doi.org/10.1155/2018/9602525
Review Article

Herbal Formula Modified Buzhong-Yiqi-Tang for Functional Constipation in Adults: A Meta-Analysis of Randomized Controlled Trials

1Department of Integrated Traditional Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, China
2Research Core Facility, West China Hospital, Sichuan University, Chengdu 610041, China

Correspondence should be addressed to Hongbo He; moc.361@999lhgcn

Received 24 August 2017; Revised 9 November 2017; Accepted 11 December 2017; Published 16 January 2018

Academic Editor: Takashi Takeda

Copyright © 2018 Hanlin Gong et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. M. Mugie, M. A. Benninga, and C. Di Lorenzo, “Epidemiology of constipation in children and adults: a systematic review,” Best Practice & Research: Clinical Gastroenterology, vol. 25, no. 1, pp. 3–18, 2011. View at Publisher · View at Google Scholar · View at Scopus
  2. Y. F. Zhao, X. Q. Ma, R. Wang et al., “Epidemiology of functional constipation and comparison with constipation-predominant irritable bowel syndrome: the Systematic Investigation of Gastrointestinal Diseases in China (SILC),” Alimentary Pharmacology & Therapeutics, vol. 34, no. 8, pp. 1020–1029, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. S. S. Rao, K. Rattanakovit, and T. Patcharatrakul, “Diagnosis and management of chronic constipation in adults,” Nature Reviews Gastroenterology & Hepatology, vol. 13, no. 5, pp. 295–305, 2016. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Wald, “Constipation advances in diagnosis and treatment,” Journal of the American Medical Association, vol. 315, no. 2, pp. 185–191, 2016. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Belsey, S. Greenfield, D. Candy, and M. Geraint, “Systematic review: impact of constipation on quality of life in adults and children,” Alimentary Pharmacology & Therapeutics, vol. 31, no. 9, pp. 938–949, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Wald, C. Scarpignato, M. A. Kamm et al., “The burden of constipation on quality of life: results of a multinational survey,” Alimentary Pharmacology & Therapeutics, vol. 26, no. 2, pp. 227–236, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. K. Dan, H. Akiyoshi, K. Munakata, H. Hasegawa, and K. Watanabe, “A Kampo (traditional Japanese herbal) medicine, Hochuekkito, pretreatment in mice prevented influenza virus replication accompanied with GM-CSF expression and increase in several defensin mRNA levels,” Pharmacology, vol. 91, no. 5-6, pp. 314–321, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. H. Gou, L. Y. Gu, B. Z. Shang, Y. Xiong, and C. Wang, “Protective effect of Bu-Zhong-Yi-Qi decoction, the water extract of Chinese traditional herbal medicine, on 5-fluorouracil-induced intestinal mucositis in mice,” Human & Experimental Toxicology, vol. 35, no. 12, pp. 1243–1251, 2016. View at Publisher · View at Google Scholar · View at Scopus
  9. X. F. Zheng, J. S. Tian, P. Liu, J. Xing, and X. M. Qin, “Analysis of the restorative effect of Bu-zhong-yi-qi-tang in the spleen-qi deficiency rat model using 1H-NMR-based metabonomics,” Journal of Ethnopharmacology, vol. 151, no. 2, pp. 912–920, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. M. He, W. Chen, M. Wang et al., “Simultaneous determination of multiple bioactive components of Bu-zhong-yi-qi-tang in rat tissues by LC–MS/MS: Application to a tissue distribution study,” Journal of Chromatography B, vol. 1044-1045, pp. 177–184, 2017. View at Publisher · View at Google Scholar · View at Scopus
  11. J. S. Ge, “Clinical observation and the gastrointestinal hormone levels of Buzhongyiqi decoction Combined with Mosapride in patients with constipation,” Journal of New Chinese Medicine, vol. 45, no. 3, pp. 70-71, 2015. View at Google Scholar
  12. H. Kobayashi, M. Ishii, S. Takeuchi et al., “Efficacy and safety of a traditional herbal medicine, hochu-ekki-to in the long-term management of Kikyo (Delicate Constitution) patients with atopic dermatitis: a 6-month, multicenter, double-blind, randomized, placebo-controlled study,” Evidence-Based Complementary and Alternative Medicine, vol. 7, no. 3, pp. 367–373, 2010. View at Publisher · View at Google Scholar · View at Scopus
  13. C. Li and J. Xin, “Study on clinical effect of Buzhong Yiqi granule combined with Duphalac treatment of functional constipation of qi deficiency type,” Clinical Medicine (Chinese), vol. 31, no. 12, pp. 119-120, 2011. View at Google Scholar
  14. M. Chen and W. Wang, “Clinical observation of modified Buzhong Yiqi Decoction on the treatment of constipation in patients with Parkinson's disease,” Chinese Journal of Integrative Medicine on Cardio/Cerebrovascular Disease, vol. 12, no. 1, pp. 59-60, 2014. View at Google Scholar
  15. Y. Duan, “Clinical observation of modified Buzhong Yiqi Decoction in treatment of elderly Patients with Qi-deficiency Type of Constipation,” Medicine information, vol. 27, no. 7, p. 323, 2014. View at Google Scholar
  16. C. Hu, Y. Zhang, and D. Wang, “Effect of Buzhong Yiqi Decoction in the treatment of elderly patients with Qi deficiency constipation,” Chinese Journal of Gerontology, vol. 32, no. 3, pp. 600-601, 2012. View at Google Scholar
  17. R. Huang, “Buzhong Yiqi Decoction in treating spleen qi deficiency type constipation in 48 cases,” Fujian Journal of Traditional Chinese Medicine, vol. 38, no. 4, p. 33, 2007. View at Google Scholar
  18. Y. Jin, “The curative effect of buzhongyiqitang decoction in the treatment of elderly Patients with deficiency constipation,” Journal of the Chinese Medical Association, vol. 30, no. 26, pp. 88–90, 2014. View at Google Scholar
  19. X. B. Li, S. X. Mao, Z. B. Tian, and J. X. Wu, “Buzhong Yiqi Decoction in the treatment of constipation in elderly patients After Operations of Femoral Rotator Fracture,” Henan Traditional Chinese Medicine, vol. 34, no. 8, pp. 1610-1611, 2014. View at Google Scholar
  20. L. P. Liu, “Clinical observation of Modified Buzhong Yiqi Decoction for 84 cases of elderly Patients with Habitual Constipation,” Chinese Journal of Integrated Traditional and Western Medicine, vol. 28, no. 9, pp. 855-856, 2008. View at Google Scholar
  21. X. Pan, “Modified Buzhong Yiqi Decoction for 20 cases of Senile Qi-deficiency Type of Constipation,” China Foreign Medical Treatment, vol. 32, no. 35, pp. 124-125, 2013. View at Google Scholar
  22. Y. Shen, “80 cases of senile constipation treated with Buzhong Yiqi Decoction,” Zhejiang Journal of Traditional Chinese Medicine, vol. 46, no. 10, p. 771, 2011. View at Google Scholar
  23. Z. Wang, X. Fang, and X. Y. Lu, “Effect of Buzhong Yiqi Decoction in the treatment of elderly patients with Qi deficiency Type of constipation,” Heilongjiang Journal of Traditional Chinese Medicine, vol. 43, no. 5, pp. 48-49, 2014. View at Google Scholar
  24. J. Wu, Q. Wang, W. Zhang, and M. Gao, “Clinical observation of modified Buzhong Yiqi Decoction in treatment of functional constipation,” Acta Chinese Medicine and Pharmacology, vol. 41, no. 5, pp. 114-115, 2013. View at Google Scholar
  25. L. Yang and C. Chu, “Clinical observation of Buzhong Yiqi Decoction in the treatment of constipation patients with acute stroke,” Journal of New Chinese Medicine, vol. 46, no. 7, pp. 36-37, 2014 (Chinese). View at Google Scholar
  26. J. Yang, “40 cases of senile habitual constipation treated by Buzhongyiqi Decoction,” Guangming Journal of Chinese Medicine, vol. 26, no. 7, pp. 1382-1383, 2011. View at Google Scholar
  27. J. Shen, C. Jiang, L. Huang, B. Wang, and P. Wang, “Observation of the Curative Effect of Buzhong Yiqi Decoction on the constipation Patients After Chemotherapy,” Heilongjiang journal of traditional Chinese medicine, vol. 43, no. 6, pp. 29-30, 2014. View at Google Scholar
  28. Y. Fu, “Clinical observation on Buzhong Yiqi Decoction for treatment of irritable bowel syndrome of constipation type in 60 cases,” Jiangsu Journal of Traditional Chinese Medicine, vol. 48, no. 6, pp. 42-43, 2016. View at Google Scholar
  29. Y. He, “Buzhong Yiqi Decoction in treatment of 150 cases of habitual constipation,” Guangming Journal of Chinese Medicine, vol. 25, no. 6, p. 975, 2010. View at Google Scholar
  30. Y. Hui and X. Li, “30 cases of patients with chronic obstructive pulmonary disease constipation treated by Buzhongyiqi Decoction,” Modern Traditional Chinese Medicine, vol. 32, no. 5, pp. 16-17, 2012. View at Google Scholar
  31. W. Song, “The Clinical Observation of modified Buzhong Yiqi Decoction in Treating with Slow Transit Constipation,” Chinese Journal of Integrated Traditional and Western Medicine, vol. 10, no. 5, pp. 56-57, 2010. View at Google Scholar
  32. W. Xu, J. Wu, J. Hu et al., “Clinical observation on constipation of qi-deficiency type by Buzhong Yiqi pills combined with biofeedback,” Practical Geriatrics, vol. 26, no. 2, pp. 127–130, 2012. View at Google Scholar
  33. J. Zhang, L. Li, J. Yan, X. Li, and S. Zhao, “Clinical observation on functional constipation (qi deficiency type) with Buzhong Yiqi decoction,” Journal of Shanxi College of Traditional Chinese Medicine, vol. 17, no. 3, pp. 42-43, 2016. View at Google Scholar
  34. S. Zheng, L. Peng, X. Lin, and N. Zhang, “Bu Zhong Yi Qi Decoction Deficency Retention Enema Combined Wesetrn Medicine Thearpy Outlet Obstruction Constipation Random parallel Contorl Study,” Journal of Practical Traditional Chinese Internal Medicine, vol. 27, no. 7, pp. 133–135, 2013. View at Google Scholar
  35. F. Deng, “Study on clinical effect of Buzhong Yiqi Decoction Combined with cisapride in the treatment of Senile Functional Constipation,” Chinese Journal of Clinical Rational Drug Use, vol. 5, no. 11, pp. 55-56, 2012. View at Google Scholar
  36. Y. Xu, The clinical study of buzhongyiqi tang combined with mosapride in treatment of qi deficiency of the chronic constipation of the elderly [M.S. Thesis], Hubei University of Traditional Chinese Medicine, Wuhan, China, 2012 (English).
  37. T. Huang, “Clinical observation of Buzhong Yiqi Decoction in treating constipation patients With Retroversioflexion of uterus,” Modern Journal of Integrated Traditional Chinese and Western Medicine, vol. 12, no. 7, pp. 710-711, 2013. View at Google Scholar
  38. J. P. T. Higgins and S. Green, Cochrane Handbook for Systematic Reviews of Interventions, Version 5.1.0, The Cochrane Collaboration, 2011. View at Publisher · View at Google Scholar
  39. Z. F. Li, J. H. Gu, and M. Hu, “Clinical observation of Modified Buzhong Yiqi Decoction for elderly Patients with Qi-deficiency Type of Constipation,” Journal of Practical Traditional Chinese Medicine, vol. 31, no. 10, pp. 900-901, 2015. View at Google Scholar
  40. G. Basilisco and M. Coletta, “Chronic constipation: A critical review,” Digestive and Liver Disease, vol. 45, no. 11, pp. 886–893, 2013. View at Publisher · View at Google Scholar · View at Scopus
  41. A. D. Markland, O. Palsson, P. S. Goode, K. L. Burgio, J. Busby-Whitehead, and W. E. Whitehead, “Association of low dietary intake of fiber and liquids with constipation: Evidence from the national health and nutrition examination survey,” American Journal of Gastroenterology, vol. 108, no. 5, pp. 796–803, 2013. View at Publisher · View at Google Scholar · View at Scopus
  42. A. C. Ford and N. C. Suares, “Effect of laxatives and pharmacological therapies in chronic idiopathic constipation: systematic review and meta-analysis,” Gut, vol. 60, no. 2, pp. 209–218, 2011. View at Publisher · View at Google Scholar · View at Scopus
  43. K. Altabas, A. Bilić, D. Jurčić et al., “The efficacy of cisapride vs. placebo and diet in patients with chronic constipation,” Collegium Antropologicum, vol. 27, no. 1, pp. 197–204, 2003. View at Google Scholar · View at Scopus
  44. J. F. Johanson and J. Kralstein, “Chronic constipation: a survey of the patient perspective,” Alimentary Pharmacology & Therapeutics, vol. 25, no. 5, pp. 599–608, 2007. View at Publisher · View at Google Scholar · View at Scopus
  45. C. Y. Ko, J. Tong, R. E. Lehman, A. A. Shelton, T. R. Schrock, and M. L. Welten, “Biofeedback is effective therapy for fecal incontinence and constipation,” JAMA Surgery, vol. 132, no. 8, pp. 829–834, 1997. View at Publisher · View at Google Scholar · View at Scopus
  46. F. Qin, J.-Y. Liu, and J.-H. Yuan, “Chaihu-Shugan-San, an oriental herbal preparation, for the treatment of chronic gastritis: A meta-analysis of randomized controlled trials,” Journal of Ethnopharmacology, vol. 146, no. 2, pp. 433–439, 2013. View at Publisher · View at Google Scholar · View at Scopus